Qualitative Evidence Synthesis (QES) for Guidelines: Paper 1-Using qualitative evidence synthesis to inform guideline scope and develop qualitative findings statements

被引:47
作者
Downe, Soo [1 ]
Finlayson, Kenneth W. [1 ]
Lawrie, Theresa A. [2 ]
Lewin, Simon A. [3 ,4 ]
Glenton, Claire [3 ]
Rosenbaum, Sarah [3 ]
Barreix, Maria [5 ]
Tuncalp, Ozge [5 ]
机构
[1] Univ Cent Lancashire, Preston, Lancs, England
[2] Evidence Based Med Consultancy Ltd, Bath, Avon, England
[3] Norwegian Inst Publ Hlth, Oslo, Norway
[4] South African Med Res Council, Hlth Syst Res Unit, Cape Town, South Africa
[5] WHO, World Bank Special Programme Res Dev & Res Traini, Dept Reprod Hlth & Res Including, UNDP,UNFPA,UNICEF, Geneva, Switzerland
关键词
Evidence-to-decision; guideline development; GRADE; GRADE-CERQual; QES; qualitative review; qualitative evidence synthesis; syntheses; qualitative methods; WHO guidelines; CARE;
D O I
10.1186/s12961-019-0467-5
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Background WHO has recognised the need to ensure that guideline processes are transparent and evidence based, and that the resulting recommendations are relevant and applicable. Along with decision-making criteria that require findings from effectiveness reviews, WHO is increasingly using evidence derived from qualitative evidence syntheses (QES) to inform the values, acceptability, equity and feasibility implications of its recommendations. This is the first in a series of three papers examining the use of QES in developing clinical and health systems guidelines. Methods WHO convened a group of methodologists involved in developing recent (2010-2018) guidelines that were informed by QES. Using a pragmatic and iterative approach that included feedback from WHO staff and other stakeholders, the group reflected on, discussed and identified key methods and research implications from designing QES and using the resulting findings in guideline development. Our aim in this paper is to (1) describe and discuss how the findings of QES can inform the scope of a guideline and (2) develop findings for key guideline decision-making criteria. Results QES resulted in the addition of new outcomes that are directly relevant to service users, a stronger evidence base for decisions about how much effective interventions and related outcomes are valued by stakeholders in a range of contexts, and a more complete database of summary evidence for guideline panels to consider, linked to decisions about values, acceptability, feasibility and equity. Conclusions Rigorously conducted QES can be a powerful means of improving the relevance of guidelines, and of ensuring that the concerns of stakeholders, at all levels of the healthcare system and from a wide range of settings, are taken into account at all stages of the process.
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相关论文
共 32 条
[1]   GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 1: Introduction [J].
Alonso-Coello, Pablo ;
Schunemann, Holger J. ;
Moberg, Jenny ;
Brignardello-Petersen, Romina ;
Akl, Elie A. ;
Davoli, Marina ;
Treweek, Shaun ;
Mustafa, Reem A. ;
Rada, Gabriel ;
Rosenbaum, Sarah ;
Morelli, Angela ;
Guyatt, Gordon H. ;
Oxman, Andrew D. .
BMJ-BRITISH MEDICAL JOURNAL, 2016, 353
[2]  
[Anonymous], 2016, The First Global Integrated Marine Assessment (World Ocean Assessment I) retrieved on the 10th of January 2020 via from
[3]  
[Anonymous], 2016, WHO LIB CATALOGUING
[4]  
[Anonymous], 2014, GLOBAL TUBERCULOSIS
[5]   The use of purposeful sampling in a qualitative evidence synthesis: A worked example on sexual adjustment to a cancer trajectory [J].
Benoot, Charlotte ;
Hannes, Karin ;
Bilsen, Johan .
BMC MEDICAL RESEARCH METHODOLOGY, 2016, 16
[6]   Applying GRADE-CERQual to qualitative evidence synthesis findings-paper 7: understanding the potential impacts of dissemination bias [J].
Booth, Andrew ;
Lewin, Simon ;
Glenton, Claire ;
Munthe-Kaas, Heather ;
Toews, Ingrid ;
Noyes, Jane ;
Rashidian, Arash ;
Berg, Rigmor C. ;
Nyakang'o, Brenda ;
Meerpohl, Joerg J. .
IMPLEMENTATION SCIENCE, 2018, 13
[7]  
Colvin CJ, 2018, IMPLEMENT SCI, V13, DOI [10.1186/s13012-017-0691-8, 10.1186/s13012-017-0693-6, 10.1186/s13012-017-0688-3, 10.1186/s13012-017-0690-9]
[8]   A systematic review of qualitative evidence on barriers and facilitators to the implementation of task-shifting in midwifery services [J].
Colvin, Christopher J. ;
de Heer, Jodie ;
Winterton, Laura ;
Mellenkamp, Milagros ;
Glenton, Claire ;
Noyes, Jane ;
Lewin, Simon ;
Rashidian, Arash .
MIDWIFERY, 2013, 29 (10) :1211-1221
[9]   What matters to women: a systematic scoping review to identify the processes and outcomes of antenatal care provision that are important to healthy pregnant women [J].
Downe, S. ;
Finlayson, K. ;
Tuncalp, O. ;
Guelmezoglu, A. Metin .
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2016, 123 (04) :529-539
[10]  
Downe S, 2018, COCHRANE DB SYST REV