Neuroendocrine Perspectives in Alopecia Areata: Does Stress Play a Role?

被引：52

作者：

Paus, Ralf ^{[1
,2
]}

Arck, Petra ^{[3
]}

机构：

[1] Med Univ Lubeck, Dept Dermatol, D-23538 Lubeck, Germany

[2] Univ Manchester, Sch Translat Med, Manchester, Lancs, England

[3] McMaster Univ, Brain Body Inst, Hamilton, ON, Canada

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2009年 / 129卷 / 06期

关键词：

CORTICOTROPIN-RELEASING HORMONE; HAIR-GROWTH; SUBSTANCE-P; DIFFERENTIAL EXPRESSION; C3H/HEJ MOUSE; TELOGEN STAGE; UP-REGULATION; HPA AXIS; SKIN; FOLLICLE;

D O I：

10.1038/jid.2009.111

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Until recently, the popular notion that psychoemotional stress can have an impact on hair growth has been treated with skepticism and assigned to the realm of folklore by many authorities. Yet it has long been appreciated that episodes of alopecia areata (AA) have occurred after severely stressful life events (Reinhold, 1960; Whitlock, 1976). This has triggered debates about whether AA should be considered a psychosomatic disorder (Misery and Rousset, 2001; Willemsen et al., 2009). Journal of Investigative Dermatology (2009) 129, 1324-1326. doi:10.1038/jid.2009.111

引用

页码：1324 / 1326

页数：4

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