Indirect bright light improves circadian rest-activity rhythm disturbances in demented patients

被引：300

作者：

VanSomeren, EJW ^{[1
]}

Kessler, A ^{[1
]}

Mirmiran, M ^{[1
]}

Swaab, DF ^{[1
]}

机构：

[1] GRAD SCH NEUROSCI, AMSTERDAM, NETHERLANDS

来源：

BIOLOGICAL PSYCHIATRY | 1997年 / 41卷 / 09期

关键词：

Alzheimer's disease; dementia; circadian rhythm disturbance; bright light; sleep; actigraphy;

D O I：

10.1016/S0006-3223(97)89928-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Light is known to be an important modulator of circadian rhythms, We tested the hypothesis that an enduring increase in the daytime environmental illumination level improves rest-activity rhythm disturbances in demented patients. Actigraphy was performed before, during, and after 4 weeks of increased illumination in the living rooms of 22 patients with dementia clinically diagnosed as probable Alzheimer's disease, multi-infarct dementia, dementia associated with alcoholism, or normal pressure hydrocephalus. The results indicated that during increased illumination, the stability of the rest-activity rhythm increased in patients with intact vision, but not in visually impaired patients. (C) 1997 Society of Biological Psychiatry.

引用

页码：955 / 963

页数：9