A short synthesis of chiral macrocyclic dioxopolyamines derived from L-proline

被引：7
|
作者：
Fang, MH
Fu, EQ [1 ]
Yuan, QA
Xue, P
Wu, CT
Chen, JH
机构：
[1] Wuhan Univ, Dept Chem, Wuhan 430072, Peoples R China
[2] Beijing Univ, Coll Chem & Mol Engn, Beijing, Peoples R China
来源：
SYNTHETIC COMMUNICATIONS | 2002年 / 32卷 / 23期
关键词：
D O I：
10.1081/SCC-120014977
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A convenient and effective synthesis of enantiomerically pure macrocyclic dioxopolyamine 3 and its derivatives 4-9 is presented. Macrocyle 3, derived from L-proline, was prepared in high overall yield and easily modified. 8 and 9 were prepared by modified Mannich reaction in good yields.
引用
收藏
页码：3629 / 3635
页数：7
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