The chromosomal passenger complex takes center stage during mitosis

被引：10

作者：

Vernos, I ^{[1
]}

机构：

[1] EMBL, Cell Biol & Biophys Program, D-69117 Heidelberg, Germany

来源：

DEVELOPMENTAL CELL | 2004年 / 7卷 / 02期

关键词：

D O I：

10.1016/j.devcel.2004.07.016

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The chromosomal passenger complex plays important roles in key mitotic events, including chromosome biorientation, the spindle assembly checkpoint, and cytokinesis. Two groups now report the identification of a novel component of the Incenp/survivin/auroraB complex (Gassmann et al., 2004; Sampath et al., 2004) and show that different subcomplexes may exist during mitosis. Exciting data support the involvement of the passenger complex in yet another key event, the assembly of the mitotic spindle.

引用

页码：145 / 146

页数：2

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