A systemic antiviral resistance-inducing protein isolated from Clerodendrum inerme Gaertn is a polynucleotide:adenosine glycosidase (ribosome-inactivating protein)

被引：50
作者：
Olivieri, F
Prasad, V
Valbonesi, P
Srivastava, S
GhosalChowdhury, P
Barbieri, L
Bolognesi, A
Stirpe, F
机构：
[1] UNIV BOLOGNA,DIPARTIMENTO PATOL SPERIMENTALE,I-40126 BOLOGNA,ITALY
[2] UNIV LUCKNOW,DEPT BOT,UNIT APPL PHYTOVIROL,LUCKNOW 226007,UTTAR PRADESH,INDIA
来源：
FEBS LETTERS | 1996年 / 396卷 / 2-3期
关键词：
ribosome-inactivating protein; polynucleotide:adenosine glycosidase; antiviral protein;
D O I：
10.1016/0014-5793(96)01089-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two systemic antiviral resistance-inducing proteins, CIP-29 and CIP-34, isolated from Clerodendrum inerme Gaertn, leaves, were tested for ribosome-inactivating properties. It was found that CIP-29 has the characteristics of a polynucleotide: adenosine glycosidase (ribosome-inactivating protein), in that it inhibits protein synthesis both in cell-free systems and, at higher concentrations, in cells, and releases adenine from ribosomes, RNA, poly(A) and DNA. As compared with other known RIPs, CIP-29 deadenylates DNA at a high rate, and induces systemic antiviral resistance in susceptible plants.
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页码：132 / 134
页数：3
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