A systemic antiviral resistance-inducing protein isolated from Clerodendrum inerme Gaertn is a polynucleotide:adenosine glycosidase (ribosome-inactivating protein)

被引：50

作者：

Olivieri, F

Prasad, V

Valbonesi, P

Srivastava, S

GhosalChowdhury, P

Barbieri, L

Bolognesi, A

Stirpe, F

机构：

[1] UNIV BOLOGNA,DIPARTIMENTO PATOL SPERIMENTALE,I-40126 BOLOGNA,ITALY

[2] UNIV LUCKNOW,DEPT BOT,UNIT APPL PHYTOVIROL,LUCKNOW 226007,UTTAR PRADESH,INDIA

来源：

FEBS LETTERS | 1996年 / 396卷 / 2-3期

关键词：

ribosome-inactivating protein; polynucleotide:adenosine glycosidase; antiviral protein;

D O I：

10.1016/0014-5793(96)01089-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two systemic antiviral resistance-inducing proteins, CIP-29 and CIP-34, isolated from Clerodendrum inerme Gaertn, leaves, were tested for ribosome-inactivating properties. It was found that CIP-29 has the characteristics of a polynucleotide: adenosine glycosidase (ribosome-inactivating protein), in that it inhibits protein synthesis both in cell-free systems and, at higher concentrations, in cells, and releases adenine from ribosomes, RNA, poly(A) and DNA. As compared with other known RIPs, CIP-29 deadenylates DNA at a high rate, and induces systemic antiviral resistance in susceptible plants.

引用

页码：132 / 134

页数：3

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