Self-assembly of precisely defined DNA nanotube superstructures using DNA origami seeds

被引：31

作者：

Mohammed, A. M. ^{[1
]}

Velazquez, L. ^{[2
]}

Chisenhall, A. ^{[1
]}

Schiffels, D. ^{[2
,5
]}

Fygenson, D. K. ^{[2
,3
]}

Schulman, R. ^{[1
,4
]}

机构：

[1] Johns Hopkins Univ, Chem & Biomol Engn, Baltimore, MD 21218 USA

[2] Univ Calif Santa Barbara, Dept Phys, Santa Barbara, CA 93106 USA

[3] Univ Calif Santa Barbara, Biomol Sci & Engn, Santa Barbara, CA 93106 USA

[4] Johns Hopkins Univ, Comp Sci, Baltimore, MD 21218 USA

[5] Nanofabricat Res Grp, Gaithersburg, MD USA

来源：

NANOSCALE | 2017年 / 9卷 / 02期

基金：

美国国家科学基金会;

关键词：

MITOTIC SPINDLE; PEPTIDE; NUCLEATION; ACTIN;

D O I：

10.1039/c6nr06983e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We demonstrate a versatile process for assembling micron-scale filament architectures by controlling where DNA tile nanotubes nucleate on DNA origami assemblies. "Nunchucks," potential mechanical magnifiers of nanoscale dynamics consisting of two nanotubes connected by a dsDNA linker, form at yields sufficient for application and consistent with models.

引用

页码：522 / 526

页数：5

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