Nonsteroidal antiinflammatory drugs: A review

被引:88
|
作者
Curry, Stephen L. [1 ]
Cogar, Steven M.
Cook, James L.
机构
[1] Univ Missouri, Coll Vet Med, Dept Vet Med & Surg, Columbia, MO 65211 USA
[2] Univ Missouri, Coll Vet Med, Comparat Orthopaed Lab, Columbia, MO 65211 USA
关键词
D O I
10.5326/0410298
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The increasing use of nonsteroidal antiinflammatory drugs (NSAIDs) in small animals has resulted in the development of new and innovative additions to this class of drugs. Examples of NSAIDs now available for use in small animals include aspirin, etodolac, carprofen, ketoprofen, meloxicam, deracoxib, and tepoxalin. The purposes of this article are to review the pathophysiology of prostaglandin synthesis and inhibition, the mechanisms of action, pharmacokinetics, pharmacological effects, and potential adverse reactions of aspirin and the newly released NSAIDs.
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页码:298 / 309
页数:12
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