An Approach to the Synthesis of Tetrahydroisoquinoline Alkaloids by Alkene Hydroamination: Synthesis of Coralydine

被引：11

作者：

Pouilhes, Annie ^{[1
]}

Baltaze, Jean-Pierre ^{[1
]}

Kouklovsky, Cyrille ^{[1
]}

机构：

[1] Univ Paris Sud, Inst Chim Mol & Mat Orsay, CNRS, UMR 8182, F-91405 Orsay, France

来源：

SYNLETT | 2013年 / 24卷 / 14期

关键词：

alkaloids; total synthesis; nitrogen; heterocycles; ASYMMETRIC-SYNTHESIS; ISOQUINOLINE ALKALOIDS; STRATEGY;

D O I：

10.1055/s-0033-1339375

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The protoberberine alkaloid coralydine was synthesized in a short sequence by a strategy including an intramolecular alkene hydroamination as the key step, followed by a Pictet-Spengler cyclization.

引用

页码：1805 / 1808

页数：4

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