An Approach to the Synthesis of Tetrahydroisoquinoline Alkaloids by Alkene Hydroamination: Synthesis of Coralydine

被引：11
|
作者：
Pouilhes, Annie [1 ]
Baltaze, Jean-Pierre [1 ]
Kouklovsky, Cyrille [1 ]
机构：
[1] Univ Paris Sud, Inst Chim Mol & Mat Orsay, CNRS, UMR 8182, F-91405 Orsay, France
来源：
SYNLETT | 2013年 / 24卷 / 14期
关键词：
alkaloids; total synthesis; nitrogen; heterocycles; ASYMMETRIC-SYNTHESIS; ISOQUINOLINE ALKALOIDS; STRATEGY;
D O I：
10.1055/s-0033-1339375
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The protoberberine alkaloid coralydine was synthesized in a short sequence by a strategy including an intramolecular alkene hydroamination as the key step, followed by a Pictet-Spengler cyclization.
引用
收藏
页码：1805 / 1808
页数：4
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