In Vitro Susceptibility Profiles of Eight Antifungal Drugs against Clinical and Environmental Strains of Phaeoacremonium

被引:10
作者
Badali, Hamid [1 ]
Khodavaisy, Sadegh [2 ,3 ]
Fakhim, Hamed [4 ]
de Hoog, G. Sybren [5 ]
Meis, Jacques F. [6 ,7 ]
Chowdhary, Anuradha [8 ]
机构
[1] Mazandaran Univ Med Sci, Sch Med, IFRC, Dept Med Mycol & Parasitol, Sari, Iran
[2] Kurdistan Univ Med Sci, Dept Med Parasitol & Mycol, Sanandaj, Iran
[3] Univ Tehran Med Sci, Dept Med Parasitol & Mycol, Tehran, Iran
[4] Mazandaran Univ Med Sci, Student Res Comm, Sari, Iran
[5] CBS KNAW Fungal Biodivers Ctr, Utrecht, Netherlands
[6] Radboud Univ Nijmegen, Med Ctr, Dept Med Microbiol, Nijmegen, Netherlands
[7] Canisius Wilhelmina Hosp, Dept Med Microbiol & Infect Dis, Nijmegen, Netherlands
[8] Univ Delhi, Vallabhbhai Patel Chest Inst, Dept Med Microbiol, Delhi 110007, India
关键词
PARASITICUM; INFECTIONS; PATIENT; DISEASE;
D O I
10.1128/AAC.01733-15
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In vitro susceptibilities of a worldwide collection of molecularly identified Phaeoacremonium strains (n = 43) belonging to seven species and originating from human and environmental sources were determined for eight antifungal drugs. Voriconazole had the lowest geometric mean MIC (0.35 mu g/ml), followed by posaconazole (0.37 mu g/ml), amphotericin B (0.4 mu g/ml), and isavuconazole (1.16 mu g/ml). Caspofungin, anidulafungin, fluconazole, and itraconazole had no activity.
引用
收藏
页码:7818 / 7822
页数:5
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