Mono-N-methylation of anilines with methanol catalyzed by a manganese pincer-complex

被引：182

作者：

Bruneau-Voisine, Antoine ^{[1
]}

Wang, Ding ^{[1
]}

Dorcet, Vincent ^{[2
]}

Roisnel, Thierry ^{[2
]}

Darcel, Christophe ^{[1
]}

Sortais, Jean-Baptiste ^{[1
,3
]}

机构：

[1] Univ Rennes 1, Inst Sci Chim Rennes, UMR CNRS 6226, Team Organometall Mat & Catalysis, 263 Ave Gen Leclerc, F-35046 Rennes, France

[2] Univ Rennes 1, Inst Sci Chim Rennes, UMR CNRS 6226, Ctr Diffractometrie X, 263 Ave Gen Leclerc, F-35046 Rennes, France

[3] Inst Univ France, 1 Rue Descartes, F-75231 Paris 05, France

来源：

JOURNAL OF CATALYSIS | 2017年 / 347卷

关键词：

Manganese; Amines; Methylation; Pincer complex; Hydrogen borrowing; CARBON-DIOXIDE; BORROWING HYDROGEN; ALPHA-ALKYLATION; AROMATIC-AMINES; STEREOSELECTIVE HYDROGENATION; REDUCTIVE METHYLATION; MECHANISTIC INSIGHTS; BOND FORMATION; C-ALKYLATION; FORMIC-ACID;

D O I：

10.1016/j.jcat.2017.01.004

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The selective mono-N-methylation of anilines derivatives was achieved under mild conditions using inexpensive methanol as Cl source. Under hydrogen borrowing conditions, using a tridentate (PNP)-P-3 manganese pre-catalyst (5 mol%), a catalytic amount of base (20 mol%), for 24 h at 120 degrees C, a large variety of anilines derivatives was methylated in good to excellent yield. Mechanistic investigations allowed us to isolate and characterize by X-ray diffraction studies a de-aromatized manganese intermediate. (C) 2017 Elsevier Inc. All rights reserved.

引用

页码：57 / 62

页数：6

共 110 条

[1] Recent development in catalytic technologies for methanol synthesis from renewable sources: A critical review [J].