Using a theragnostic approach in juvenile idiopathic arthritis

Introduction: Central to the concept of theragnostics is the elegant aim of precision medicine from the fusion of therapy and diagnostics. Recent advances in the field of juvenile idiopathic arthritis clinical therapy points towards a step forward in the aspect of targeted therapy, particularly in the context of systemic juvenile idiopathic arthritis. Areas covered: Juvenile idiopathic arthritis is a complex set of heterogenous diseases. Precision medicine will serve to dissect through this heterogeneity to provide targeted therapy for patients. This review will serve to educate the reader on recent success of targeted therapy in systemic juvenile idiopathic arthritis and how the field is impacted. Expert opinion: A direct link between diagnosis and therapy is required for further progress in targeted therapy of juvenile idiopathic arthritis. Elucidation of pathogenic immune subsets is relevant to this endeavor and the platforms that may help revolutionize the discovery of the elusive target.