Targeting Drosophila eye development

被引：14
作者：
Jemc, Jennifer
Rebay, Ilaria
机构：
[1] MIT, Dept Biol, Cambridge, MA 02142 USA
[2] Univ Chicago, Ben May Inst Canc Res, Chicago, IL 60637 USA
来源：
GENOME BIOLOGY | 2006年 / 7卷 / 07期
关键词：
D O I：
10.1186/gb-2006-7-7-226
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
In order to understand the role of transcription factors in particular developmental processes it is necessary to know their target genes. A combination of bioinformatics, comparative expression profiling and microarray-based epistasis experiments has recently identified new targets of Eyeless, a key transcription factor in Drosophila retinal determination.
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页数：3
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共 17 条
  • [1] Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome
    Berman, BP
    Nibu, Y
    Pfeiffer, BD
    Tomancak, P
    Celniker, SE
    Levine, M
    Rubin, GM
    Eisen, MB
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (02) : 757 - 762
  • [2] Dachshund and eyes absent proteins form a complex and function synergistically to induce ectopic eye development in Drosophila
    Chen, R
    Amoui, M
    Zhang, ZH
    Mardon, G
    [J]. CELL, 1997, 91 (07) : 893 - 903
  • [3] Dokucu ME, 1996, DEVELOPMENT, V122, P4139
  • [4] Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog
    Glise, B
    Miller, CA
    Crozatier, M
    Halbisen, MA
    Wise, S
    Olson, DJ
    Vincent, A
    Blair, SS
    [J]. DEVELOPMENTAL CELL, 2005, 8 (02) : 255 - 266
  • [5] The Drosophila ortholog of the human Wnt inhibitor factor Shifted controls the diffusion of lipid-modified Hedgehog
    Gorfinkiel, N
    Sierra, J
    Callejo, A
    Ibañez, C
    Guerrero, I
    [J]. DEVELOPMENTAL CELL, 2005, 8 (02) : 241 - 253
  • [6] Halder G, 1998, DEVELOPMENT, V125, P2181
  • [7] Kawakami K, 2000, BIOESSAYS, V22, P616, DOI 10.1002/1521-1878(200007)22:7<616::AID-BIES4>3.0.CO
  • [8] 2-R
  • [9] Analysis of the eye developmental pathway in Drosophila using DNA microarrays
    Michaut, L
    Flister, S
    Neeb, M
    White, KP
    Certa, U
    Gehring, WJ
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (07) : 4024 - 4029
  • [10] Genome-wide identification of direct targets of the Drosophila retinal determination protein Eyeless
    Ostrin, EJ
    Li, YM
    Hoffman, K
    Liu, J
    Wang, KQ
    Zhang, L
    Mardon, G
    Chen, R
    [J]. GENOME RESEARCH, 2006, 16 (04) : 466 - 476
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