PATHOMORPHOLOGICAL CHANGES IN VITAL ORGANS OF BUFFALOES (BUBALUS BUBALIS) NATURALLY INFECTED WITH LEPTOSPIROSIS

The pathological aspects of leptospirosis were studied in 7 buffaloes with a conclusive diagnosis of the disease, as confirmed by MAT Main necropsy lesions in kindey included congestion, few shrunken/atrophied glomeruli, periglomerular infiltration of mononuclear cells, tubular degeneration and cast in tubular lumen were common findings. The hepatic lesions were characterized by distortion/disruption of hepatic cord, individualization of hepatocytes, varying degree of degenerative/necrotic changes in hepatocytes, presence of stray necrotic foci, mild congestion and mononuclear cell infiltration in portal areas. Pulmonary lesions comprised of congestion, focal area of alveolar edema, alveolar consolidation, emphysema, mononuclear cell infiltration in peri-bronchial/bronchiolar areas and foci of interalveolar thickened septae. Varying degree of congestion, lymphocytic depletion and hemosiderine pigment depositions were the histopathological features of splenic lesions.