Validity, responsiveness and minimum clinically important difference of the incremental shuttle walk in idiopathic pulmonary fibrosis: a prospective study

被引：31

作者：

Nolan, Claire M. ^{[1
,2
]}

Delogu, Veronica ^{[1
]}

Maddocks, Matthew ^{[3
]}

Patel, Suhani ^{[1
]}

Barker, Ruth E. ^{[1
]}

Jones, Sarah E. ^{[1
]}

Kon, Samantha S. C. ^{[1
,4
]}

Maher, Toby M. ^{[2
,5
]}

Cullinan, Paul ^{[2
]}

Man, William D-C ^{[1
,2
]}

机构：

[1] Royal Brompton & Harefield NHS Fdn Trust, Harefield Hosp, Harefield Pulm Rehabil & Muscle Res Lab, Harefield, Middx, England

[2] Imperial Coll, Natl Heart & Lung Inst, London, England

[3] Kings Coll London, Cicely Saunders Inst Palliat Care Policy & Rehabi, London, England

[4] Hillingdon Hosp NHS Fdn Trust, Dept Resp Med, London, England

[5] Royal Brompton & Harefield NHS Fdn Trust, Dept Interstitial Lung Dis Unit, London, England

来源：

THORAX | 2018年 / 73卷 / 07期

基金：

美国国家卫生研究院;

关键词：

incremental shuttle walk test; IPF; COPD;

D O I：

10.1136/thoraxjnl-2017-210589

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The incremental shuttle walk (ISW) is well validated in COPD but limited psychometric data restrict its use in idiopathic pulmonary fibrosis (IPF). Study 1: 50 patients performed the ISW and 6min walk test (6MWT). Study 2: 72 patients completed the ISW before and after pulmonary rehabilitation (PR). The ISW correlated strongly with 6MWT distance (r=0.81,p<0.0001). Mean (95%confidence interval) improvement in ISW with PR was 54 (38 to 70)m with an effect size of 0.29. Distribution-based and anchor-based minimum clinically important difference (MCID) estimates ranged from 31 to 46m. The ISW is valid and responsive in IPF, with an anchor-based MCID estimate similar to that observed in chronic obstructive pulmonary disease. Trial registration number Pre-results; NCT02530736, NCT02436278.

引用

页码：680 / 682

页数：3

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