Before and after the spindle assembly checkpoint - An APC/C point of view

被引:13
作者
de Gramont, Armand
Ganier, Olivier
Cohen-Fix, Orna
机构
[1] NIDDK, Mol & Cellular Biol Lab, NIH, Bethesda, MD USA
[2] Univ Paris 06, CNRS, UMR 7098, Paris, France
关键词
anaphase promoting complex; APC/C cyclin A; Emi1; Rassf1A; Mad3; Nek2A; UbcH10; spindle assembly checkpoint;
D O I
10.4161/cc.5.18.3219
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
On May 17-21, 2006 the Cold Spring Harbor Laboratory meeting on the cell cycle reunited over 350 researchers to discuss new findings in the cell cycle field. A common thread that connected numerous presentations was the regulation of the anaphase promoting complex/cyclosome (APC/C). This was also the main theme of the lecture given by the keynote speaker, Marc Kirschner (Harvard), who talked about "The unexpected importance of UbcH10 in both the G(1)/S transition and the initiation of anaphase", and it is also the main focus in this summary.
引用
收藏
页码:2168 / 2171
页数:4
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