14-3-3 Proteins in Glutamatergic Synapses

被引：32

作者：

Zhang, Jiajing ^{[1
]}

Zhou, Yi ^{[1
]}

机构：

[1] Florida State Univ, Coll Med, Dept Biomed Sci, Tallahassee, FL 32306 USA

来源：

NEURAL PLASTICITY | 2018年 / 2018卷

关键词：

LONG-TERM POTENTIATION; RECEPTOR TRAFFICKING; SYNAPTIC PLASTICITY; KAINATE RECEPTORS; NMDA RECEPTORS; PHOSPHORYLATION; KINASE; INACTIVATION; RIM1-ALPHA; 14-3-3-EPSILON;

D O I：

10.1155/2018/8407609

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The 14-3-3 proteins are a family of proteins that are highly expressed in the brain and particularly enriched at synapses. Evidence accumulated in the last two decades has implicated 14-3-3 proteins as an important regulator of synaptic transmission and plasticity. Here, we will review previous and more recent research that has helped us understand the roles of 14-3-3 proteins at glutamatergic synapses. A key challenge for the future is to delineate the 14-3-3-dependent molecular pathways involved in regulating synaptic functions.

引用

页数：6

共 61 条

[1] 14-3-3 PROTEINS ON THE MAP [J].

AITKEN, A .

TRENDS IN BIOCHEMICAL SCIENCES, 1995, 20 (03) :95-97

[2] Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling [J].

Angrand, Pierre-Olivier ;

Segura, Inmaculada ;

Voelkel, Pamela ;

Ghidelli, Sonja ;

Terry, Rebecca ;

Brajenovic, Miro ;

Vintersten, Kristina ;

Klein, Ruediger ;

Superti-Furga, Giulio ;

Drewes, Gerard ;

Kuster, Bernhard ;

Bouwmeester, Tewis ;

Acker-Palmer, Amparo .

MOLECULAR & CELLULAR PROTEOMICS, 2006, 5 (12) :2211-2227

[3] Next-generation transgenic mice for optogenetic analysis of neural circuits analysis of neural circuits [J].

Asrican, Brent ;

Augustine, George J. ;

Berglund, Ken ;

Chen, Susu ;

Chow, Nick ;

Deisseroth, Karl ;

Feng, Guoping ;

Gloss, Bernd ;

Hira, Riichiro ;

Hoffmann, Carolin ;

Kasai, Haruo ;

Katarya, Malvika ;

Kim, Jinsook ;

Kudolo, John ;

Lee, Li Ming ;

Lo, Shun Qiang ;

Mancuso, James ;

Matsuzaki, Masanori ;

Nakajima, Ryuichi ;

Qiu, Li ;

Tan, Gregory ;

Tang, Yanxia ;

Ting, Jonathan T. ;

Tsuda, Sachiko ;

Wen, Lei ;

Zhang, Xuying ;

Zhao, Shengli .

FRONTIERS IN NEURAL CIRCUITS, 2013, 7

[4] Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain [J].

Baxter, HC ;

Liu, WG ;

Forster, JL ;

Aitken, A ;

Fraser, JR .

NEUROSCIENCE, 2002, 109 (01) :5-14

[5] Nuclear sequestration of β-subunits by Rad and Rem is controlled by 14-3-3 and calmodulin and reveals a novel mechanism for Ca2+ channel regulation [J].

Béguin, P ;

Mahalakshmi, RN ;

Nagashima, K ;

Cher, DHK ;

Ikeda, H ;

Yamada, Y ;

Seino, Y ;

Hunziker, W .

JOURNAL OF MOLECULAR BIOLOGY, 2006, 355 (01) :34-46

[6] 14-3-3 proteins in the nervous system [J].

Berg, D ;

Holzmann, C ;

Riess, O .

NATURE REVIEWS NEUROSCIENCE, 2003, 4 (09) :752-762

[7] Identification of cofilin and LIM-domain-containing protein kinase 1 as novel interaction partners of 14-3-3ζ [J].

Birkenfeld, J ;

Betz, H ;

Roth, D .

BIOCHEMICAL JOURNAL, 2003, 369 :45-54

[8] Leonardo, a Drosophila 14-3-3 protein involved in learning, regulates presynaptic function [J].

Broadie, K ;

Rushton, E ;

Skoulakis, EMC ;

Davis, RL .

NEURON, 1997, 19 (02) :391-402

[9] Targeting 14-3-3 protein, difopein induces apoptosis of human glioma cells and suppresses tumor growth in mice [J].

Cao, Weidong ;

Yang, Xiaoliang ;

Zhou, Jie ;

Teng, Zenghui ;

Cao, Lei ;

Zhang, Xiang ;

Fei, Zhou .

APOPTOSIS, 2010, 15 (02) :230-241

[10] Growth Factor-Dependent Trafficking of Cerebellar NMDA Receptors via Protein Kinase B/Akt Phosphorylation of NR2C [J].

Chen, Bo-Shiun ;

Roche, Katherine W. .

NEURON, 2009, 62 (04) :471-478

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