Celiac disease in African-Americans

被引:29
作者
Brar, Pardeep [1 ]
Lee, Ann R. [1 ]
Lewis, Suzanne K. [1 ]
Bhagat, Govind [1 ]
Green, Peter H. R. [1 ]
机构
[1] Columbia Univ, Coll Phys & Surg, Dept Med, New York, NY USA
关键词
African-American; celiac disease; compliance; gluten-free diet; HLA DQ typing;
D O I
10.1007/s10620-005-9000-5
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Celiac disease is generally under diagnosed in the United States and it is unclear whether the disease is encountered in ethnic minorities. Our purpose is to describe a case series of African-American patients with celiac disease. Nine (1.3%) African-American patients with celiac disease were identified from a prospectively generated database of 700 patients with biopsy proven celiac disease and seen between 1981 and 2004. Females predominated, with seven, compared to two males. Diarrhea was the presentation in only two patients, while three presented with iron deficiency anemia. One third had at least one autoimmune disease. Compliance with a gluten-free diet, the only medical therapy of this disease, was poor. Only four patients adhered strictly to the diet. Celiac disease occurs in African-Americans and may well be underdiagnosed. Special attention needs to be given to methods that encourage adherence to the diet in minority groups.
引用
收藏
页码:1012 / 1015
页数:4
相关论文
共 28 条
[1]  
al-Hassany M, 1975, J Trop Pediatr Environ Child Health, V21, P178
[2]   Coeliac disease in north-eastern Libya [J].
Al-Tawaty, AI ;
Elbargathy, SM .
ANNALS OF TROPICAL PAEDIATRICS, 1998, 18 (01) :27-30
[3]   Narrative review: Celiac disease: Understanding a complex autoimmune disorder [J].
Alaedini, A ;
Green, PHR .
ANNALS OF INTERNAL MEDICINE, 2005, 142 (04) :289-298
[4]   Effect of gender on the manifestations of celiac disease: Evidence for greater malabsorption in men [J].
Bai, D ;
Brar, P ;
Holleran, S ;
Ramakrishnan, R ;
Green, PHR .
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2005, 40 (02) :183-187
[5]   NEED FOR FOLLOW-UP IN CELIAC-DISEASE [J].
BARDELLA, MT ;
MOLTENI, N ;
PRAMPOLINI, L ;
GIUNTA, AM ;
BALDASSARRI, AR ;
MORGANTI, D ;
BIANCHI, PA .
ARCHIVES OF DISEASE IN CHILDHOOD, 1994, 70 (03) :211-213
[6]   Factors relating to compliance with a gluten-free diet in patients with coeliac disease: comparison of white Caucasian and South Asian patients [J].
Butterworth, JR ;
Banfield, LM ;
Iqbal, TH ;
Cooper, BT .
CLINICAL NUTRITION, 2004, 23 (05) :1127-1134
[7]   Long-term follow-up of celiac adults on gluten-free diet: Prevalence and correlates of intestinal damage [J].
Ciacci, C ;
Cirillo, M ;
Cavallaro, R ;
Mazzacca, G .
DIGESTION, 2002, 66 (03) :178-185
[8]   AGA technical review on celiac sprue [J].
Ciclitira, PJ .
GASTROENTEROLOGY, 2001, 120 (06) :1526-1540
[9]   Advice available on the Internet for people with coeliac disease: an evaluation of the quality of websites [J].
England, CY ;
Nichols, AM .
JOURNAL OF HUMAN NUTRITION AND DIETETICS, 2004, 17 (06) :547-559
[10]   Compliance with gluten-free diet in adolescents with screening-detected celiac disease:: A 5-year follow-up study [J].
Fabiani, E ;
Taccari, LM ;
Rätsch, IM ;
Di Giuseppe, S ;
Coppa, GV ;
Catassi, C .
JOURNAL OF PEDIATRICS, 2000, 136 (06) :841-843