Bimetallic nickel-ferrite nanorod particles: greener synthesis using rosemary and its biomedical efficiency

被引:58
作者
Alijani, Hajar Q. [1 ]
Pourseyedi, Shahram [2 ]
Torkzadeh-Mahani, Masoud [3 ]
Seifalian, Alexander [4 ]
Khatami, Mehrdad [1 ,5 ]
机构
[1] Bam Univ Med Sci, NanoBioElectrochem Res Ctr, Bam 7616914115, Iran
[2] Shahid Bahonar Univ Kerman, Res & Technol Inst Plant Prod, Kerman, Iran
[3] Grad Univ Adv Technol, Inst Sci & High Technol & Environm Sci, Dept Biotechnol, Kerman, Iran
[4] Nanotechnol & Regenerat Med Commercializat Ctr, London, England
[5] Kerman Univ Med Sci, Cell Therapy & Regenerat Med Comprehens Ctr, Kerman, Iran
关键词
Nickel-ferrite (NiFe2O4) nanorods; rosemary; biosynthesis; cytotoxicity;
D O I
10.1080/21691401.2019.1699830
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Nickel-ferrite (NiFe2O4) nanorods particles (NRP) was biosynthesised for the first time by the Rosemary Extract. The NRP was fully characterised, including the type, nanostructure and physicochemical properties of using XRD, HRTEM, FeSEM, XPS, FTIR and VSM. TEM confirmed rod-shaped nano-sized particles with average sizes ranging from 10 nm to 28 nm. The EDAX Analysis showed the presence of iron, nickel, oxygen, and carbon. XRD analysis confirmed the synthesis of NiFe2O4 crystals. XPS curves showed photoelectron for iron, oxygen and nickel. EDS showed the atomic, weight percentages ratios of Ni(12%): Fe(24%) and: O(48) are close to the theoretical value (Ni: Fe:O = 1:2:4), of bimetallic magnetic NiFe2O4 NRP. NiFe2O4 NRP had cytotoxicity effect on MCF-7 cells survival which suggests that NiFe2O4 NRP can be used as a new class of anticancer agent in design novel cancer therapy research. [GRAPHICS] .
引用
收藏
页码:242 / 251
页数:10
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