Role of autologous platelet-rich plasma in treatment of femoral neck fractures

被引:0
作者
Ren, Weihua [1 ]
Wang, Fengchun [1 ]
Sun, Lei [1 ]
Gao, Weipeng [2 ]
Ye, Hong [3 ]
Jia, Kun [4 ]
Gao, Lei [1 ]
机构
[1] Taian City Cent Hosp, Dept Spinal Joint Surg, 28 Longtan Rd, Tai An 271000, Shandong, Peoples R China
[2] Taian City Cent Hosp, Dept Recovery Sect, Tai An, Shandong, Peoples R China
[3] Taian City Cent Hosp, Dept Pathol, Tai An, Shandong, Peoples R China
[4] Taian City Cent Hosp, Dept Pediat Surg, Tai An, Shandong, Peoples R China
关键词
Platelet-rich plasma (PRP); femoral neck fractures; closed reduction and internal fixation; outcomes; INTRACAPSULAR HIP-FRACTURES; SPORTS-MEDICINE; FEMUR FRACTURE; NATIONAL DATA; HEMIARTHROPLASTY; MANAGEMENT; ENHANCEMENT; OUTCOMES; SURGERY; GRAFTS;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background: Few studies have investigated the outcome of the use of platelet-rich plasma (PRP) in the treatment of femoral neck fractures. The aim of this study was to evaluate the efficacy of PRP in management of femoral neck fractures. Materials and methods: This study included 64 cases in PRP group and 64 cases in control group. After clinical evaluation, patients in control group only underwent closed reduction and internal fixation and patients in PRP group received addition of PRP to internal fixation. Results: Mean length of hospital stay was 13.7 days in the PRP group and 18.1 days in the control group, which was found significant difference between the two groups (P = 0.042). Similarly, the PRP group obtained a shorter union time, compared to the control group (P = 0.005). No statistically significant differences were observed in functional outcomes regards HHS or VAS between the 2 groups (Table 2). There was no difference in the presence of complications (P > 0.05) using Fisher's exact test. Conclusions: Although no differences in functional outcomes were observed between the groups, PRP could obtain a decreased hospital stay and bone union time.
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收藏
页码:1610 / 1614
页数:5
相关论文
共 25 条
[1]  
BONNAIRE F, 1995, UNFALLCHIRURG, V98, P259
[2]   Closed reduction and internal fixation versus total hip arthroplasty for displaced femoral neck fracture [J].
Cao Liehu ;
Wang Bin ;
Li Ming ;
Song Shaojun ;
Weng Weizong ;
Li Haihang ;
Su Jiacan .
CHINESE JOURNAL OF TRAUMATOLOGY, 2014, 17 (02) :63-68
[3]   Femoral Neck Fractures: Current Management [J].
Florschutz, Anthony V. ;
Langford, Joshua R. ;
Haidukewych, George J. ;
Koval, Kenneth J. .
JOURNAL OF ORTHOPAEDIC TRAUMA, 2015, 29 (03) :121-129
[4]   Platelet-rich therapy in the treatment of patients with hip fractures: a single centre, parallel group, participant-blinded, randomised controlled trial [J].
Griffin, Xavier L. ;
Achten, Juul ;
Parsons, Nick ;
Costa, Matt L. .
BMJ OPEN, 2013, 3 (06)
[5]   Platelet-rich Plasma: Current Concepts and Application in Sports Medicine [J].
Hall, Michael P. ;
Band, Phillip A. ;
Meislin, Robert J. ;
Jazrawi, Laith M. ;
Cardone, Dennis A. .
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS, 2009, 17 (10) :602-608
[6]   PLATELET ALPHA-GRANULES [J].
HARRISON, P ;
CRAMER, EM .
BLOOD REVIEWS, 1993, 7 (01) :52-62
[7]   Cemented hemiarthroplasty or hip replacement for intracapsular neck of femur fracture? A comparison of 7732 matched patients using national data [J].
Jameson, Simon S. ;
Lees, Deborah ;
James, Philip ;
Johnson, Andrew ;
Nachtsheim, Christopher ;
McVie, James L. ;
Rangan, Amar ;
Muller, Scott D. ;
Reed, Mike R. .
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 2013, 44 (12) :1940-1944
[8]   Cemented versus cementless hemiarthroplasty for intracapsular neck of femur fracture-A comparison of 60,848 matched patients using national data [J].
Jameson, Simon S. ;
Jensen, Cyrus D. ;
Elson, David W. ;
Johnson, Andrew ;
Nachtsheim, Christopher ;
Rangan, Amar ;
Muller, Scott D. ;
Reed, Mike R. .
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 2013, 44 (06) :730-734
[9]   Clinical experience, primary results and pitfalls in the treatment of intracapsular hip fractures with the Targon® FN locking plate [J].
Korver, Rob J. P. ;
Wieland, Arvid W. J. ;
Kaarsemaker, Sjoerd ;
Nieuwenhuis, Jeroen J. ;
Janzing, Heinrich M. J. .
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 2013, 44 (12) :1926-1929
[10]   OUTCOMES AFTER DISPLACED FRACTURES OF THE FEMORAL-NECK - A METAANALYSIS OF 106 PUBLISHED REPORTS [J].
LUYAO, GL ;
KELLER, RB ;
LITTENBERG, B ;
WENNBERG, JE .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1994, 76A (01) :15-25