Likelihood ratios: A powerful tool for biological test's interpretation

被引:2
作者
Delacour, H. [1 ]
Francois, N. [2 ]
Servonnet, A. [1 ]
Gentile, A. [2 ]
Roche, B. [1 ]
机构
[1] Hop Instruct Armees Begin, Fed Biol Clin, F-94163 St Mande, France
[2] Hop Instruct Armees Robert Picque, Fed Anesthesie Reanimat, F-33998 Bordeaux, France
来源
IMMUNO-ANALYSE & BIOLOGIE SPECIALISEE | 2009年 / 24卷 / 02期
关键词
Likelihood ratios; Diagnostic test; Interpretation; DIAGNOSIS; THEOREM;
D O I
10.1016/j.immbio.2009.01.002
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Diagnostic tests are an essential part of clinical. medicine, assisting the clinician in formulating diagnoses and judging disease severity, prognosis and likely responses to therapy. Correct use of a test's diagnostic information requires its performance characteristic to be determined through rigorous evaluation in clinical settings. Traditionally, sensitivity, specificity and predictive values have been widely instituted in the medical literature to characterise test performance. However, in more and more publications, likelihood ratios replace these indices. The aim of this paper is to present the concept of likelihood ratios and to illustrate their application through cases studies. (C) 2009 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:92 / 99
页数:8
相关论文
共 7 条
[1]  
Bayes T., 1763, PHILOS T ROY SOC LON, V53, P418, DOI DOI 10.1098/RSTL.1763.0053
[2]  
FAGAN TJ, 1975, NEW ENGL J MED, V293, P257
[3]   Evidence base of clinical diagnosis - Evaluation of diagnostic procedures [J].
Knottnerus, JA ;
van Weel, C ;
Muris, JWM .
BMJ-BRITISH MEDICAL JOURNAL, 2002, 324 (7335) :477-480
[4]  
Nendaz MR, 2004, REV MAL RESPIR, V21, P394
[5]   Prospective evaluation of the '4Ts' score and particle gel immunoassay specific to heparin/PF4 for the diagnosis of heparin-induced thrombocytopenia [J].
Pouplard, C. ;
Gueret, P. ;
Fouassier, M. ;
Ternisien, C. ;
Trossaert, M. ;
Regina, S. ;
Gruel, Y. .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2007, 5 (07) :1373-1379
[6]  
TABOULET P, 2007, 25030F10 EMC
[7]  
Warkentin Theodore E, 2003, Curr Hematol Rep, V2, P148