An improved method for the synthesis of DL-3-(2-furyl)alanine

被引：0

作者：

Kitagawa, T

Akiyama, N

机构：

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1997年 / 45卷 / 11期

关键词：

DL-3-(2-furyl)alanine; furan derivative; unnatural amino acid; 2-(bromomethyl)furan; diethyl formamidomalonate; 2-furanmethanol;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

DL-3-(2-Furyl)alanine (1) was prepared by the condensation of 2-(bromomethyl)furan (7) with diethyl formamidomalonate (2), followed by the traditional saponification-decarboxylation techniques.

引用

页码：1865 / 1866

页数：2

共 6 条

[1] CHEMISTRY OF 2-(CHLOROMETHYL)FURANS - REACTION OF 2-(CHLOROMETHYL)FURANS WITH AQUEOUS POTASSIUM CYANIDE AND OTHER NUCLEOPHILES [J].

DIVALD, S ;

CHUN, MC ;

JOULLIE, MM .

JOURNAL OF ORGANIC CHEMISTRY, 1976, 41 (17) :2835-2846

[2]

KELLER R, Patent No. 3738908

[3]

KITAGAWA T, 1994, CHEM PHARM BULL, V42, P1931

[4]

KRETZSCHMAR G, Patent No. 3820302

[5] Intramolecular anodic olefin coupling reactions and the use of electron-rich [J].

New, DG ;

Tesfai, Z ;

Moeller, KD .

JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (05) :1578-1598

[6] A STUDY OF UNNATURAL AMINO ACIDS AND THEIR PEPTIDES .I. SYNTHESIS OF DL-BETA-(2-FURYL)ALPHA-ALANINE [J].

WATANABE, H ;

KUWATA, S ;

NAKAJIMA, S ;

KOSHIDA, K ;

HAYASHI, M .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1965, 38 (09) :1461-+

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