Molecular Separation with Organic Solvent Nanofiltration: A Critical Review

被引:1348
作者
Marchetti, Patrizia [1 ]
Solomon, Maria F. Jimenez [1 ]
Szekely, Gyorgy [1 ]
Livingston, Andrew G. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem Engn & Chem Technol, London SW7 2AZ, England
基金
英国工程与自然科学研究理事会;
关键词
ACTIVE PHARMACEUTICAL INGREDIENTS; COMPOSITE REVERSE-OSMOSIS; MEMBRANE FORMATION PARAMETERS; FILM NANOCOMPOSITE MEMBRANES; FILLED POLYDIMETHYLSILOXANE PDMS; PHASE INVERSION PARAMETERS; STABLE POLYMERIC MEMBRANES; SRNF TRANSPORT MECHANISM; SOLUTION-DIFFUSION MODEL; ATOMIC-FORCE MICROSCOPY;
D O I
10.1021/cr500006j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Separation processes play a remarkable role in the chemical and pharmaceutical industries, where they account for 40-70% of both capital and operating costs.1 Organic syntheses in the chemical and pharmaceutical industry are frequently performed in organic solvents and consist of products with high added value that should be removed from the organic solvents. Additionally, organic solvents, used as raw materials, for chemical syntheses, and as cleaning agents, have to be recovered or discarded at the end of the process. According to the transport mechanism, membrane separation is based on both size exclusion and additional effects, characteristic of the molecular level. UF and MF are characterized by a sieving transport mechanism through pores of significant dimension, therefore described by the pore-flow theory, while RO is characterized by the solution diffusion transport mechanism, because the free volume is so small, that it is in the range of thermal motion of the polymer chains that form the membrane.
引用
收藏
页码:10735 / 10806
页数:72
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