Neuropeptides and their receptors in the immune system

被引:0
|
作者
van Hagen, PM
Hofland, LJ
ten Bokum, AMC
Lichtenauer-Kaligis, EGR
Kwekkeboom, DJ
Ferone, D
Lamberts, SWJ
机构
[1] Erasmus Univ, Dept Immunol, NL-3000 DR Rotterdam, Netherlands
[2] Erasmus Univ, Dept Internal Med 3, NL-3000 DR Rotterdam, Netherlands
[3] Erasmus Univ, Dept Nucl Med, NL-3000 DR Rotterdam, Netherlands
关键词
immune system; somatostatin; substance P;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Neuropeptides and their receptors are produced and expressed by neuroendocrine tissues and function as neurotransmitters and/or mediators of well-defined hormonal activities in specific tissues and cells. However, neuropeptides and their receptors are also found in the immune system, and various neuropeptides are involved in both systems. In this review we discuss the role of two of these neuropeptides, somatostatin and substance P, with regard to their receptor expression in the human immune system and their role in the diagnosis and treatment of immune-mediated diseases.
引用
收藏
页码:15 / 22
页数:8
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