Immune status: Normal expression of MHC class I in the placenta and what is expected in clones

被引：7
|
作者：
Ellis, SA [1 ]
机构：
[1] Inst Food Res, Inst Anim Hlth, Newbury RG20 7NN, Berks, England
来源：
CLONING AND STEM CELLS | 2004年 / 6卷 / 02期
关键词：
D O I：
10.1089/1536230041372355
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Major histocompatibility complex (MHC) class I genes are highly polymorphic, widely expressed genes that play a vital role in immune responses. Because of their involvement in tissue transplant rejection there has been much interest in their expression during pregnancy. This review examines the evidence for their role in livestock reproduction, and speculates that the process of creating clones may modify their expression with deleterious results.
引用
收藏
页码：121 / 125
页数：5
相关论文
共 50 条
  • [31] Expression of MHC class I, MHC class II, and cancer germline antigens in neuroblastoma
    Matthias Wölfl
    Achim A. Jungbluth
    Federico Garrido
    Teresa Cabrera
    Sharon Meyen-Southard
    Rüdiger Spitz
    Karen Ernestus
    Frank Berthold
    Cancer Immunology, Immunotherapy, 2005, 54 : 400 - 406
  • [32] The effect on MHC class II expression and apoptosis in placenta by IFNγ administration
    Liu, Z
    Chen, Y
    Yang, Y
    Peng, JP
    CONTRACEPTION, 2002, 65 (02) : 177 - 184
  • [33] MHC class I antigens, immune surveillance, and tumor immune escape
    Garcia-Lora, A
    Algarra, I
    Garrido, F
    JOURNAL OF CELLULAR PHYSIOLOGY, 2003, 195 (03) : 346 - 355
  • [34] Selective upregulation of MHC class I expression in metastatic colonies derived from tumor clones of a murine fibrosarcoma
    Pedrinaci, S
    Algarra, I
    Lora, AG
    Gaforio, JJ
    Perez, M
    Garrido, F
    INTERNATIONAL JOURNAL OF CLINICAL & LABORATORY RESEARCH, 1999, 29 (04): : 166 - 173
  • [35] EXPRESSION OF CLASS-I AND CLASS-II MHC ANTIGENS IN NORMAL AND TRANSPLANTED HUMAN-LUNG
    TAYLOR, PM
    ROSE, ML
    YACOUB, M
    TRANSPLANTATION PROCEEDINGS, 1989, 21 (01) : 451 - 452
  • [36] THE MHC CLASS-I ANTIGEN EXPRESSION IN THE RAT PLACENTA FOLLOWING NATURAL MATING VS EMBRYO TRANSFER
    KANBOURSHAKIR, A
    MACPHERSON, TA
    ARMSTRONG, DT
    KUNZ, HW
    GILL, TJ
    LABORATORY INVESTIGATION, 1991, 64 (01) : A110 - A110
  • [37] IMMUNE INTERFERON REGULATES MHC CLASS-I GENE-EXPRESSION AT A POSTTRANSCRIPTIONAL LEVEL
    GUENTHER, W
    KARR, RW
    GINDER, GD
    CLINICAL RESEARCH, 1987, 35 (03): : A417 - A417
  • [38] HORSE CDNA CLONES ENCODING 2 MHC CLASS-I GENES
    BARBIS, DP
    MAHER, JK
    STANEK, J
    KLAUNBERG, BA
    ANTCZAK, DF
    IMMUNOGENETICS, 1994, 40 (02) : 163 - 163
  • [39] Immunotherapy for cancer with downregulated MHC class I expression
    Cheng, WF
    Hung, CF
    Lin, KY
    Ling, M
    He, L
    Wu, TC
    INTERNATIONAL JOURNAL OF CANCER, 2002, : 132 - 133
  • [40] THE REGULATION AND EXPRESSION OF MHC CLASS-I GENES
    DAVID-WATINE, B
    ISRAEL, A
    KOURILSKY, P
    IMMUNOLOGY TODAY, 1990, 11 (08): : 286 - 292
12345