Immune status: Normal expression of MHC class I in the placenta and what is expected in clones

被引：7
|
作者：
Ellis, SA [1 ]
机构：
[1] Inst Food Res, Inst Anim Hlth, Newbury RG20 7NN, Berks, England
来源：
CLONING AND STEM CELLS | 2004年 / 6卷 / 02期
关键词：
D O I：
10.1089/1536230041372355
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Major histocompatibility complex (MHC) class I genes are highly polymorphic, widely expressed genes that play a vital role in immune responses. Because of their involvement in tissue transplant rejection there has been much interest in their expression during pregnancy. This review examines the evidence for their role in livestock reproduction, and speculates that the process of creating clones may modify their expression with deleterious results.
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页码：121 / 125
页数：5
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