Physicians' use of computerized clinical decision supports to improve medication management in the elderly - the Seniors Medication Alert and Review Technology intervention

被引:25
作者
Alagiakrishnan, Kannayiram [1 ]
Wilson, Patricia [2 ]
Sadowski, Cheryl A. [3 ]
Rolfson, Darryl [1 ]
Ballermann, Mark [4 ,5 ]
Ausford, Allen [6 ,7 ]
Vermeer, Karla [7 ]
Mohindra, Kunal [8 ]
Romney, Jacques [9 ]
Hayward, Robert S. [10 ]
机构
[1] Univ Alberta, Dept Med, Div Geriatr Med, Edmonton, AB, Canada
[2] Univ Alberta, Dept Med, Edmonton, AB, Canada
[3] Univ Alberta, Fac Pharm & Pharmaceut Sci, Edmonton, AB T6G 2N8, Canada
[4] Univ Alberta, Alberta Hlth Serv, Chief Med Informat Off, Edmonton, AB, Canada
[5] Univ Alberta, Dept Med, Div Crit Care, Edmonton, AB, Canada
[6] Univ Alberta, Dept Family Med, Edmonton, AB, Canada
[7] Univ Alberta, Edmonton, AB, Canada
[8] Univ Alberta, EMR, Alberta Hlth Serv Informat Syst, Edmonton, AB, Canada
[9] Univ Alberta, Dept Med, Div Endocrinol, Edmonton, AB, Canada
[10] Univ Alberta, Div Gen Internal Med, Edmonton, AB, Canada
关键词
Beers' Criteria; medication management; polypharmacy; Cockcroft-Gault formula; clinical decision support; ADVERSE DRUG-REACTIONS; INAPPROPRIATE MEDICATION; CREATININE CLEARANCE; SYSTEMS; CARE; IMPACT; RECONCILIATION; POLYPHARMACY; HEALTH; TIME;
D O I
10.2147/CIA.S94126
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background: Elderly people (aged 65 years or more) are at increased risk of polypharmacy (five or more medications), inappropriate medication use, and associated increased health care costs. The use of clinical decision support (CDS) within an electronic medical record (EMR) could improve medication safety. Methods: Participatory action research methods were applied to preproduction design and development and postproduction optimization of an EMR-embedded CDS implementation of the Beers' Criteria for medication management and the Cockcroft-Gault formula for estimating glomerular filtration rates (GFR). The "Seniors Medication Alert and Review Technologies" (SMART) intervention was used in primary care and geriatrics specialty clinics. Passive (chart messages) and active (order-entry alerts) prompts exposed potentially inappropriate medications, decreased GFR, and the possible need for medication adjustments. Physician reactions were assessed using surveys, EMR simulations, focus groups, and semi-structured interviews. EMR audit data were used to identify eligible patient encounters, the frequency of CDS events, how alerts were managed, and when evidence links were followed. Results: Analysis of subjective data revealed that most clinicians agreed that CDS appeared at appropriate times during patient care. Although managing alerts incurred a modest time burden, most also agreed that workflow was not disrupted. Prevalent concerns related to clinician accountability and potential liability. Approximately 36% of eligible encounters triggered at least one SMART alert, with GFR alert, and most frequent medication warnings were with hypnotics and anticholinergics. Approximately 25% of alerts were overridden and similar to 15% elicited an evidence check. Conclusion: While most SMART alerts validated clinician choices, they were received as valuable reminders for evidence-informed care and education. Data from this study may aid other attempts to implement Beers' Criteria in ambulatory care EMRs.
引用
收藏
页码:73 / 81
页数:9
相关论文
共 29 条
  • [1] The extent and importance of unintended consequences related to computerized provider order entry
    Ash, Joan S.
    Sittig, Dean F.
    Poon, Eric G.
    Guappone, Kenneth
    Campbell, Emily
    Dykstra, Richard H.
    [J]. JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION, 2007, 14 (04) : 415 - 423
  • [2] The unintended consequences of computerized provider order entry: Findings from a mixed methods exploration
    Ash, Joan S.
    Sittig, Dean F.
    Dykstra, Richard
    Campbell, Emily
    Guappone, Kenneth
    [J]. International Journal of Medical Informatics, 2009, 78 (SUPPL. 1) : S69 - S76
  • [3] Hospitalisations caused by adverse drug reactions (ADR): a meta-analysis of observational studies
    Beijer, HJM
    de Blaey, CJ
    [J]. PHARMACY WORLD & SCIENCE, 2002, 24 (02): : 46 - 54
  • [4] Functional Range of Creatinine Clearance for Renal Drug Dosing: A Practical Solution to the Controversy of Which Weight to Use in the Cockcroft-Gault Equation
    Brown, Daniel L.
    Masselink, Andrew J.
    Lalla, Christina D.
    [J]. ANNALS OF PHARMACOTHERAPY, 2013, 47 (7-8) : 1039 - 1044
  • [5] PREDICTION OF CREATININE CLEARANCE FROM SERUM CREATININE
    COCKCROFT, DW
    GAULT, MH
    [J]. NEPHRON, 1976, 16 (01) : 31 - 41
  • [6] Association between Glomerular Filtration Rate and Adverse Drug Reactions in Elderly Hospitalized Patients The Role of the Estimating Equation
    Corsonello, Andrea
    Pedone, Claudio
    Lattanzio, Fabrizia
    Onder, Graziano
    Incalzi, Raffaele Antonelli
    [J]. DRUGS & AGING, 2011, 28 (05) : 379 - 390
  • [7] American Geriatrics Society Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults
    Fick, Donna
    Semla, Todd
    Beizer, Judith
    Dombrowski, Robert
    Brandt, Nicole
    DuBeau, Catherine E.
    Flanagan, Nina
    Hanlon, Joseph
    Hollmann, Peter
    Linnebur, Sunny
    Nau, David
    Rehm, Bob
    Sandhu, Satinderpal
    Steinman, Michael
    [J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2012, 60 (04) : 616 - 631
  • [8] Potentially inappropriate medication use and healthcare expenditures in the US community-dwelling elderly
    Fu, Alex Z.
    Jiang, Jenny Z.
    Reeves, Jaxk H.
    Fincham, Jack E.
    Liu, Gordon G.
    Perri, Matthew, III
    [J]. MEDICAL CARE, 2007, 45 (05) : 472 - 476
  • [9] Adverse drug events in ambulatory care
    Gandhi, TK
    Weingart, SN
    Borus, J
    Seger, AC
    Peterson, J
    Burdick, E
    Seger, DL
    Shu, K
    Federico, F
    Leape, LL
    Bates, DW
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (16) : 1556 - 1564
  • [10] Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes
    Gnjidic, Danijela
    Hilmer, Sarah N.
    Blyth, Fiona M.
    Naganathan, Vasi
    Waite, Louise
    Seibel, Markus J.
    McLachlan, Andrew J.
    Cumming, Robert G.
    Handelsman, David J.
    Le Couteur, David G.
    [J]. JOURNAL OF CLINICAL EPIDEMIOLOGY, 2012, 65 (09) : 989 - 995