Decarboxylative Knoevenagel-Type Reactions on Tetronamides: Synthesis of 5-Ylidene-4-Amino-2(5H)-Furanones

被引：5

作者：

Ear, Alexandre ^{[1
,2
]}

Toum, Valerie ^{[1
,2
]}

Thorimbert, Serge ^{[1
,2
]}

Dechoux, Luc ^{[1
,2
]}

机构：

[1] Univ Paris 06, Sorbonne Univ, Inst Parisien Chim Mol, CNRS,UMR 8232, F-75005 Paris, France

[2] CNRS, Inst Parisien Chim Mol, UMR 8232, F-75005 Paris, France

来源：

SYNLETT | 2014年 / 25卷 / 12期

关键词：

Knoevenagel-Doebner reaction; -enaminoesters; tetronamides; 4-amino-2(5H)-furanones; basidalin; VINYLOGOUS URETHANE APPROACH; THERMAL REARRANGEMENT; STEREOSELECTIVE-SYNTHESIS; RING TRANSFORMATION; PRACTICAL SYNTHESIS; FACILE SYNTHESIS; DOEBNER REACTION; OKADAIC ACID; ESTERS; CONSTRUCTION;

D O I：

10.1055/s-0034-1378276

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A detailed account regarding the synthesis of 5-ylidene-2(5H)-furanones is given. The key step is a decarboxylative Knoevenagel-type reaction of tetronamides with various -functionalized aldehydes. The synthesis of protected basidalin is presented.

引用

页码：1713 / 1716

页数：4

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