Neural and behavioural responses to face-likeness of objects in adolescents with autism spectrum disorder

被引：20

作者：

Akechi, Hironori ^{[1
,2
]}

Kikuchi, Yukiko ^{[1
,3
]}

Tojo, Yoshikuni ^{[3
]}

Osanai, Hiroo ^{[4
]}

Hasegawa, Toshikazu ^{[5
]}

机构：

[1] Japan Soc Promot Sci, Tokyo, Japan

[2] Tokyo Denki Univ, Div Informat Syst Design, Saitama, Japan

[3] Ibaraki Univ, Coll Educ, Ibaraki, Japan

[4] Musashino Higashi Ctr Educ & Res, Tokyo, Japan

[5] Univ Tokyo, Dept Cognit & Behav Sci, Tokyo 1538902, Japan

来源：

SCIENTIFIC REPORTS | 2014年 / 4卷

基金：

日本学术振兴会;

关键词：

EARLY RECOGNITION; PERCEPTION; CHILDREN; ATTENTION; STIMULI; BRAIN; ADULTS; IMPAIRMENT; INSIGHTS; INFANTS;

D O I：

10.1038/srep03874

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Numerous studies have revealed atypical face processing in autism spectrum disorders (ASD) characterized by social interaction and communication difficulties. This study investigated sensitivity to face-likeness in ASD. In Experiment 1, we found a strong positive correlation between the face-likeness ratings of non-face objects in the ASD (11-19 years old) and the typically developing (TD) group (9-21 years old). In Experiment 2 (the scalp-recorded event-related potential experiment), the participants of both groups (ASD, 12-19 years old; TD, 12-18 years old) exhibited an enhanced face-sensitive N170 amplitude to a face-like object. Whereas the TD adolescents showed an enhanced N170 during the face-likeness judgements, adolescents with ASD did not. Thus, both individuals with ASD and TD individuals have a perceptual and neural sensitivity to face-like features in objects. When required to process face-like features, a face-related brain system reacts more strongly in TD individuals but not in individuals with ASD.

引用

页数：7

共 62 条

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