MR IMAGING OF ACUTE DISSEMINATED ENCEPHALOMYELITIS AND MULTIPLE SCLEROSIS IN CHILDREN. A REVIEW

被引:0
作者
Zoltan Patay [1 ]
机构
[1] Univ Tennessee, St Jude Childrens Res Hosp, Neuroradiol Sect, Dept Radiol Sci,Hlth Sci Ctr,Coll Med, Memphis, TN 38105 USA
来源
IDEGGYOGYASZATI SZEMLE-CLINICAL NEUROSCIENCE | 2009年 / 62卷 / 3-4期
关键词
magnetic resonance imaging; acute disseminated encephalomyelitis; multiple sclerosis; central nervous system demyelination; MYCOPLASMA-PNEUMONIAE INFECTION; DIAGNOSTIC-CRITERIA; DEMYELINATING DISEASE; NEUROMYELITIS-OPTICA; DIFFUSE SCLEROSIS; MCDONALD CRITERIA; VIRUS-INFECTION; NERVOUS-SYSTEM; MASS LESION; CHILDHOOD;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Inflammatory diseases of the central nervous system (CNS) are relatively rare in children, but their relevance to public health is considerable due to frequent and significant long term morbidity and even mortality. As in adults, acute disseminated encephalomyelitis (ADEM) and multiple sclerosis (MS) and their variants are the most common entities in this group of pathologies in the pediatric patient population. Recent efforts have focused on establishing standardized diagnostic criteria schemes to facilitate the diagnosis and differential diagnosis of these diseases, however especially with multiple sclerosis those have not been fully validated yet for disease occurring in children. In recent decades the role of MRI has been constantly increasing in the diagnostic work-up of suspected inflammatory diseases of the CNS as well as in the follow-up of patients with confirmed disease. Currently, MRI is the first-line diagnostic imaging modality in ADEM and MS and is fully integrated in the most widely used diagnostic criteria schemes, but it has a key role in clinical therapeutic research trials as well. This paper provides an update on the current concepts and strategies of MRI in inflammatory diseases of the CNS, as well as a review of the imaging semiology of the various disease entities and variants with emphasis on clinical and imaging particularities relevant to the pediatric patient population.
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页码:77 / 89
页数:13
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