Encapsulation and co-precipitation processes with supercritical fluids: Fundamentals and applications

被引：293

作者：

Cocero, Maria Jose ^{[1
]}

Martin, Angel ^{[1
]}

Mattea, Facundo ^{[1
]}

Varona, Salima ^{[1
]}

机构：

[1] Univ Valladolid, Fac Ciencias, Dept Ingn Quim & Tecnol Medio Ambiente, E-47011 Valladolid, Spain

来源：

JOURNAL OF SUPERCRITICAL FLUIDS | 2009年 / 47卷 / 03期

关键词：

Particle formation; Supercritical fluid; Encapsulation; Co-precipitation; Review; RAPID EXPANSION; SOLVENT IMPREGNATION; CONTROLLED-RELEASE; PHASE-BEHAVIOR; DRUG; MICROENCAPSULATION; CRYSTALLINITY; PRECIPITATION; POLYMERS; NANOPARTICLES;

D O I：

10.1016/j.supflu.2008.08.015

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The formulation of natural substances together with a biocompatible or biodegradable carrier material to form composites or encapsulates has a great relevance for pharmaceutical, cosmetic and food industries. Several precipitation methods with supercritical fluids can be successfully adapted to produce these materials. This article presents a review of the main aspects of supercritical encapsulation and co-precipitation processes, focused on a process mechanisms description as well as of the types of materials that can be formulated with them. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：546 / 555

页数：10

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