Encapsulation and co-precipitation processes with supercritical fluids: Fundamentals and applications

被引：289
作者：
Cocero, Maria Jose [1 ]
Martin, Angel [1 ]
Mattea, Facundo [1 ]
Varona, Salima [1 ]
机构：
[1] Univ Valladolid, Fac Ciencias, Dept Ingn Quim & Tecnol Medio Ambiente, E-47011 Valladolid, Spain
来源：
JOURNAL OF SUPERCRITICAL FLUIDS | 2009年 / 47卷 / 03期
关键词：
Particle formation; Supercritical fluid; Encapsulation; Co-precipitation; Review; RAPID EXPANSION; SOLVENT IMPREGNATION; CONTROLLED-RELEASE; PHASE-BEHAVIOR; DRUG; MICROENCAPSULATION; CRYSTALLINITY; PRECIPITATION; POLYMERS; NANOPARTICLES;
D O I：
10.1016/j.supflu.2008.08.015
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The formulation of natural substances together with a biocompatible or biodegradable carrier material to form composites or encapsulates has a great relevance for pharmaceutical, cosmetic and food industries. Several precipitation methods with supercritical fluids can be successfully adapted to produce these materials. This article presents a review of the main aspects of supercritical encapsulation and co-precipitation processes, focused on a process mechanisms description as well as of the types of materials that can be formulated with them. (C) 2008 Elsevier B.V. All rights reserved.
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收藏
页码：546 / 555
页数：10
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