Two faces of caspase-8

被引：2

作者：

Barnhart, BC ^{[1
]}

Peter, ME ^{[1
]}

机构：

[1] Univ Chicago, Ben May Inst Canc Res, Chicago, IL 60637 USA

来源：

NATURE IMMUNOLOGY | 2002年 / 3卷 / 10期

关键词：

D O I：

10.1038/ni1002-896

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A deficit of caspase-8 should presumably lead to over-activation of lymphocytes. A recent report in Nature from Lenardo's group, however, describes humans with a severe caspase-8 deficiency whose T cells, counter-intuitively, have impaired activation abilities.

引用

页码：896 / 898

页数：4

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