The syndemic effects of mental ill health, household hunger, and intimate partner violence on adherence to antiretroviral therapy among pregnant women living with HIV in Yaounde, Cameroon

被引:5
作者
Cordoba, Evette [1 ,2 ]
Parcesepe, Angela M. [3 ,4 ]
Gallis, John A. [5 ,6 ]
Headley, Jennifer [5 ]
Soffo, Claudian
Tchatchou, Berenger [7 ]
Hembling, John [8 ]
Baumgartner, Joy Noel [5 ]
机构
[1] Univ North Carolina Chapel Hill, Dept Epidemiol, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
[2] Columbia Univ, Sch Nursing, New York, NY USA
[3] Univ North Carolina Chapel Hill, Dept Maternal & Child Hlth, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27599 USA
[4] Univ North Carolina Chapel Hill, Carolina Populat Ctr, Chapel Hill, NC 27599 USA
[5] Duke Univ, Duke Global Hlth Inst, Durham, NC USA
[6] Duke Univ, Dept Biostat & Bioinformat, Durham, NC USA
[7] Catholic Relief Serv, Ndjamena, Chad
[8] Catholic Relief Serv, Baltimore, MD USA
关键词
TO-CHILD TRANSMISSION; SUB-SAHARAN AFRICA; FOOD INSECURITY; POSITIVE WOMEN; PMTCT SERVICES; MIDDLE-INCOME; DEPRESSION; PREVENTION; NONADHERENCE; CARE;
D O I
10.1371/journal.pone.0246467
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background This research advances understanding of interrelationships among three barriers to adherence to antiretroviral therapy (ART) among pregnant women living with HIV (WLWH) in Cameroon: probable common mental disorders (CMD), intimate partner violence (IPV), and hunger. Methods The sample included 220 pregnant WLWH in Cameroon. Multivariable modified Poisson regression was conducted to assess the relationship between IPV, hunger, and CMD on ART adherence. Results Almost half (44%) of participants recently missed/mistimed an ART dose. Probable CMD was associated with greater risk of missed/mistimed ART dose (aRR 1.5 [95% CI 1.1, 1.9]). Hunger was associated with greater risk of missed/mistimed ART dose among those who reported IPV (aRR 1.9 [95% CI 1.2, 2.8]), but not among those who did not (aRR 0.8 [95% CI 0.2, 2.3]). Conclusion Suboptimal ART adherence, CMD, and IPV were common among pregnant WLWH in Cameroon. Pregnant WLWH experiencing IPV and hunger may be especially vulnerable to suboptimal ART adherence.
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页数:13
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