The utility of twins in developmental cognitive neuroscience research: How twins strengthen the ABCD research design

被引：65
作者：
Iacono, William G. [1 ]
Heath, Andrew C. [2 ]
Hewitt, John K. [3 ]
Neale, Michael C. [4 ]
Banich, Marie T. [3 ]
Luciana, Monica M. [1 ]
Madden, Pamela A. [2 ]
Barch, Deanna M. [2 ]
Bjork, James M. [4 ]
机构：
[1] Univ Minnesota, Minneapolis, MN 55455 USA
[2] Washington Univ, St Louis, MO USA
[3] Univ Colorado Boulder, Boulder, CO USA
[4] Virginia Commonwealth Univ, Richmond, VA 23284 USA
来源：
DEVELOPMENTAL COGNITIVE NEUROSCIENCE | 2018年 / 32卷
关键词：
Twins; Heritability; Environment; Substance use; Brain structure; Brain function; MEASURED-ENVIRONMENT INTERACTION; MOLECULAR-GENETIC BASIS; SUBCORTICAL BRAIN VOLUMES; ADOLESCENT SUBSTANCE USE; ILLICIT DRUG-DEPENDENCE; GENOME-WIDE ASSOCIATION; CORTICAL SURFACE-AREA; PSYCHOPHYSIOLOGICAL ENDOPHENOTYPES; COMMON LIABILITY; P300; AMPLITUDE;
D O I：
10.1016/j.dcn.2017.09.001
中图分类号：
B844 [发展心理学（人类心理学）];
学科分类号：
040202 ;
摘要：
The ABCD twin study will elucidate the genetic and environmental contributions to a wide range of mental and physical health outcomes in children, including substance use, brain and behavioral development, and their interrelationship. Comparisons within and between monozygotic and dizygotic twin pairs, further powered by multiple assessments, provide information about genetic and environmental contributions to developmental associations, and enable stronger tests of causal hypotheses, than do comparisons involving unrelated children. Thus a sub-study of 800 pairs of same-sex twins was embedded within the overall Adolescent Brain and Cognitive Development (ABCD) design. The ABCD Twin Hub comprises four leading centers for twin research in Minnesota, Colorado, Virginia, and Missouri. Each site is enrolling 200 twin pairs, as well as singletons. The twins are recruited from registries of all twin births in each State during 2006-2008. Singletons at each site are recruited following the same school-based procedures as the rest of the ABCD study. This paper describes the background and rationale for the ABCD twin study, the ascertainment of twin pairs and implementation strategy at each site, and the details of the proposed analytic strategies to quantify genetic and environmental influences and test hypotheses critical to the aims of the ABCD study.
引用
收藏
页码：30 / 42
页数：13
相关论文
共 184 条
[1]   Cannabinoid Receptor Genotype Moderation of the Effects of Childhood Physical Abuse on Anhedonia and Depression [J].
Agrawal, Arpana ;
Nelson, Elliot C. ;
Littlefield, Andrew K. ;
Bucholz, Kathleen K. ;
Degenhardt, Louisa ;
Henders, Anjali K. ;
Madden, Pamela A. F. ;
Martin, Nicholas G. ;
Montgomery, Grant W. ;
Pergadia, Michele L. ;
Sher, Kenneth J. ;
Heath, Andrew C. ;
Lynskey, Michael T. .
ARCHIVES OF GENERAL PSYCHIATRY, 2012, 69 (07) :732-740
[2]   A different paradigm for the initial colonisation of Sahul [J].
Allen, Jim ;
O'Connell, James F. .
ARCHAEOLOGY IN OCEANIA, 2020, 55 (01) :1-14
[3]   The Mid-Atlantic Twin Registry [J].
Anderson, LS ;
Beverly, WT ;
Corey, LA ;
Murrelle, L .
TWIN RESEARCH, 2002, 5 (05) :449-455
[4]   Heritability of brain activity related to response inhibition: A longitudinal genetic study in adolescent twins [J].
Anokhin, Andrey P. ;
Golosheykin, Simon ;
Grant, Julia D. ;
Heath, Andrew C. .
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, 2017, 115 :112-124
[5]   Neural Correlates of Response Inhibition in Adolescents Prospectively Predict Regular Tobacco Smoking [J].
Anokhin, Andrey P. ;
Golosheykin, Simon .
DEVELOPMENTAL NEUROPSYCHOLOGY, 2016, 41 (1-2) :22-37
[6]   General and substance-specific predictors of young adult nicotine dependence, alcohol use disorder, and problem behavior: Replication in two samples [J].
Bailey, J. A. ;
Samek, D. R. ;
Keyes, M. A. ;
Hill, K. G. ;
Hicks, B. M. ;
McGue, M. ;
Iacono, W. G. ;
Epstein, M. ;
Catalano, R. F. ;
Haggerty, K. P. ;
Hawkins, J. D. .
DRUG AND ALCOHOL DEPENDENCE, 2014, 138 :161-168
[7]   A Demonstration of the Generalizability of Twin-based Research on Antisocial Behavior [J].
Barnes, J. C. ;
Boutwell, Brian B. .
BEHAVIOR GENETICS, 2013, 43 (02) :120-131
[8]   The heritability of life events: An adolescent twin and adoption study [J].
Bemmels, Heather R. ;
Burt, S. Alexandra ;
Legrand, Lisa N. ;
Iacono, William G. ;
McGue, Matt .
TWIN RESEARCH AND HUMAN GENETICS, 2008, 11 (03) :257-265
[9]   Heritability of Neuropsychological Measures in Schizophrenia and Nonpsychiatric Populations: A Systematic Review and Meta-analysis [J].
Blokland, Gabriella A. M. ;
Mesholam-Gately, Raquelle I. ;
Toulopoulou, Timothea ;
del Re, Elisabetta C. ;
Lam, Max ;
DeLisi, Lynn E. ;
Donohoe, Gary ;
Walters, James T. R. ;
Seidman, Larry J. ;
Petryshen, Tracey L. .
SCHIZOPHRENIA BULLETIN, 2017, 43 (04) :788-800
[10]   Genetic and Environmental Influences on Neuroimaging Phenotypes: A Meta-Analytical Perspective on Twin Imaging Studies [J].
Blokland, Gabriella A. M. ;
de Zubicaray, Greig I. ;
McMahon, Katie L. ;
Wright, Margaret J. .
TWIN RESEARCH AND HUMAN GENETICS, 2012, 15 (03) :351-371
12345678910