NEUROMODULATION OF EPILEPTIC FOCI IN PATIENTS WITH NON-LESIONAL REFRACTORY MOTOR EPILEPSY

被引：45

作者：

Luisa Velasco, Ana ^{[1
]}

Velasco, Francisco ^{[1
]}

Velasco, Marcos ^{[1
]}

Maria Nunez, Jose ^{[1
]}

Trejo, David ^{[1
]}

Garcia, Israel ^{[1
]}

机构：

[1] Hosp Gen Mexico City, Unit Stereotact Funct Neurosurg & Radiosurg, Mexico City, DF, Mexico

来源：

INTERNATIONAL JOURNAL OF NEURAL SYSTEMS | 2009年 / 19卷 / 03期

关键词：

Extratemporal epilepsy; motor seizures; motor cortex stimulation; neuromodulation; DEEP BRAIN-STIMULATION; TERM ELECTRICAL-STIMULATION; VAGUS NERVE-STIMULATION; CEREBELLAR STIMULATION; INTRACTABLE EPILEPSY; SEIZURES; SURGERY; COMPLICATIONS; HIPPOCAMPUS; SUBACUTE;

D O I：

10.1142/S0129065709001914

中图分类号：

TP18 [人工智能理论];

学科分类号：

081104 ; 0812 ; 0835 ; 1405 ;

摘要：

We report two cases of chronic therapeutic stimulation of epileptic foci localized in motor areas. Case 1 is an adolescent with supplementary motor area seizures whose intracranial recordings showed a right SMA focus. Case 2 is a female teenager with primary motor seizures originating in the right motor cortex in the hand area as shown by her intracranial recordings and cortical mapping. Both had apparently normal MRI. Chronic stimulation of the epileptic focus decreased the number of seizures more than 90% the seizure number while preserving motor function. None of the patients had side effects. Neuromodulation is proposed as a safe, efficient surgical alternative for motor seizure control.

引用

页码：139 / 147

页数：9

共 38 条

[1] Vagus nerve stimulation therapy after failed cranial surgery for intractable epilepsy: Results from the vagus nerve stimulation therapy patient outcome registry [J].

Amar, AP ;

Apuzzo, MLJ ;

Liu, CY .

NEUROSURGERY, 2004, 55 (05) :1086-1092

[2]

Asztely F, 2007, J NEUROL NEUROSUR PS, V78, P605, DOI 10.1136/jnnp.2006.098244

[3] Dichotic listening test in Spanish:: Pairs of disyllabic words [J].

Azañón-Gracia, E ;

Sebastián-Gallés, N .

REVISTA DE NEUROLOGIA, 2005, 41 (11) :657-663

[4] ELECTROPHYSIOLOGICAL STUDIES OF LONG-TERM ELECTRICAL-STIMULATION OF CEREBELLUM IN MONKEYS [J].

BABB, TL ;

SOPER, HV ;

LIEB, JP ;

BROWN, WJ ;

OTTINO, CA ;

CRANDALL, PH .

JOURNAL OF NEUROSURGERY, 1977, 47 (03) :353-365

[5] Are complications less common in deep brain stimulation than in ablative procedures for movement disorders? [J].

Blomstedt, Patric ;

Hariz, Marwan I. .

STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 2006, 84 (2-3) :72-81

[6] Deep brain stimulation in patients with refractory temporal lobe epilepsy [J].

Boon, Paul ;

Vonck, Kristl ;

De Herdt, Veerle ;

Van Dycke, Annelies ;

Goethals, Maarten ;

Goossens, Lut ;

Van Zandijcke, Michel ;

De Smedt, Tim ;

Dewaele, Isabelle ;

Achten, Rik ;

Wadman, Wytse ;

Dewaele, Frank ;

Caemaert, Jacques ;

Van Roost, Dirk .

EPILEPSIA, 2007, 48 (08) :1551-1560

[7]

CASCINO GD, 1994, EPILEPSIA, V42, P889

[8]

CONOLLY ES, 2002, FUNDAMENTALS OPERATI, P533

[9] CHRONIC CEREBELLAR STIMULATION IN EPILEPSY [J].

COOPER, IS ;

AMIN, I ;

RIKLAN, M ;

WALTZ, JM ;

POON, TP .

ARCHIVES OF NEUROLOGY, 1976, 33 (08) :559-570

[10] Development of the quality of life in epilepsy inventory for adolescents: The QOLIE-AD-48 [J].

Cramer, JA ;

Westbrook, LE ;

Devinsky, O ;

Perrine, K ;

Glassman, MB ;

Camfield, C .

EPILEPSIA, 1999, 40 (08) :1114-1121

← 1 2 3 4 →