NEUROMODULATION OF EPILEPTIC FOCI IN PATIENTS WITH NON-LESIONAL REFRACTORY MOTOR EPILEPSY

被引：45

作者：

Luisa Velasco, Ana ^{[1
]}

Velasco, Francisco ^{[1
]}

Velasco, Marcos ^{[1
]}

Maria Nunez, Jose ^{[1
]}

Trejo, David ^{[1
]}

Garcia, Israel ^{[1
]}

机构：

[1] Hosp Gen Mexico City, Unit Stereotact Funct Neurosurg & Radiosurg, Mexico City, DF, Mexico

来源：

INTERNATIONAL JOURNAL OF NEURAL SYSTEMS | 2009年 / 19卷 / 03期

关键词：

Extratemporal epilepsy; motor seizures; motor cortex stimulation; neuromodulation; DEEP BRAIN-STIMULATION; TERM ELECTRICAL-STIMULATION; VAGUS NERVE-STIMULATION; CEREBELLAR STIMULATION; INTRACTABLE EPILEPSY; SEIZURES; SURGERY; COMPLICATIONS; HIPPOCAMPUS; SUBACUTE;

D O I：

10.1142/S0129065709001914

中图分类号：

TP18 [人工智能理论];

学科分类号：

081104 ; 0812 ; 0835 ; 1405 ;

摘要：

We report two cases of chronic therapeutic stimulation of epileptic foci localized in motor areas. Case 1 is an adolescent with supplementary motor area seizures whose intracranial recordings showed a right SMA focus. Case 2 is a female teenager with primary motor seizures originating in the right motor cortex in the hand area as shown by her intracranial recordings and cortical mapping. Both had apparently normal MRI. Chronic stimulation of the epileptic focus decreased the number of seizures more than 90% the seizure number while preserving motor function. None of the patients had side effects. Neuromodulation is proposed as a safe, efficient surgical alternative for motor seizure control.

引用

页码：139 / 147

页数：9

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