Synthesis and cytotoxicity studies of cyclohepta[b]indoles, benzo[6,7]cyclohepta[1,2-b]indoles, indeno[1,2-b]indoles, and benzo[a]carbazoles

被引：35
|
作者：
Hong, Bor-Cherng [1 ]
Jiang, Yea-Fen
Chang, Yi-Ling
Lee, Shiow-Ju
机构：
[1] Natl Chung Cheng Univ, Dept Chem & Biochem, Chiayi 621, Taiwan
[2] Natl Hlth Res Inst, Div Biotechnol & Pharmaceut Res, Taipei, Taiwan
来源：
JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2006年 / 53卷 / 03期
关键词：
indole; hydrazines; hydrazones; cytotoxicity; antineoplastic;
D O I：
10.1002/jccs.200600086
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Synthesis and biological evaluation of various tricyclic and tetracyclic indoles are described. A number of these compounds possess in vitro activity against human nasopharyngeal carcinoma (HONE-1) and gastric adenocarcinoma (NUGC-3) cell lines.
引用
收藏
页码：647 / 662
页数：16
相关论文
共 50 条
  • [31] Cascade process for direct synthesis of indeno[1,2-b]furans and indeno[1,2-b]pyrroles from diketene and ninhydrin
    Rezvanian, Atieh
    Moradi, Fatemeh
    Zadsirjan, Vahideh
    Mohammadnejad, Masoumeh
    Heravi, Majid M.
    MOLECULAR DIVERSITY, 2020, 24 (04) : 1313 - 1325
  • [32] SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF SOME 5H-BENZO[4,5]CYCLOHEPTA[1,2-B]PYRIDINE DERIVATIVES
    VANDERSTELT, C
    HOFMAN, PS
    FUNCKE, ABH
    NAUTA, WT
    ARZNEIMITTEL-FORSCHUNG, 1968, 18 (06): : 756 - +
  • [33] Synthesis of indeno[1,2-b]pyridines and indeno[1,2-b] thieno-[3,2-e]pyridines
    Geies, AA
    El-Dean, AMK
    BULLETIN OF THE POLISH ACADEMY OF SCIENCES-CHEMISTRY, 1997, 45 (04): : 381 - 390
  • [34] Cascade process for direct synthesis of indeno[1,2-b]furans and indeno[1,2-b]pyrroles from diketene and ninhydrin
    Atieh Rezvanian
    Fatemeh Moradi
    Vahideh Zadsirjan
    Masoumeh Mohammadnejad
    Majid M. Heravi
    Molecular Diversity, 2020, 24 : 1313 - 1325
  • [35] Synthesis of the indeno[1,2-b]indole core of janthitrem B
    Fresia, Marvin
    Dierks, Alexandra
    Jones, Peter G.
    Lindel, Thomas
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 21 (45) : 9065 - 9069
  • [36] Acenaphtho[1,2-b]Indoles Synthesis Using SBA-Pr-SO3H
    Ziarani, Ghodsi Mohammadi
    Mirhosseyni, Marziesadat
    Kiani-Amiri, Fatemeh
    Badiei, Alireza
    CHEMISTRY AFRICA-A JOURNAL OF THE TUNISIAN CHEMICAL SOCIETY, 2024, 7 (09): : 4713 - 4718
  • [37] Synthesis of Cyclohepta[b]indoles by (4+3) Cycloaddition of 2-Vinylindoles or 4H-Furo[3,2-b]indoles with Oxyallyl Cations
    Pirovano, Valentina
    Brambilla, Elisa
    Moretti, Andrea
    Rizzato, Silvia
    Abbiati, Giorgio
    Nava, Donatella
    Rossi, Elisabetta
    JOURNAL OF ORGANIC CHEMISTRY, 2020, 85 (05): : 3265 - 3276
  • [38] Comparative Studies on Electronic Spectra and Redox Behaviors of Isomeric Benzo[1,2-b:4,5-b′]difurans and Benzo[1,2-b:5,4-b′]difurans
    Hayashi, Naoto
    Saito, Yoko
    Higuchi, Hiroyuki
    Suzuki, Kengo
    JOURNAL OF PHYSICAL CHEMISTRY A, 2009, 113 (18): : 5342 - 5347
  • [39] Synthesis and crystal structure determination of 6,7-dihydro-2-methoxy-4-(substituted)-5H-benzo[6,7]cyclohepta[1,2-b]pyridine-3-carbonitrile
    Moustafa, A. M.
    Girgis, A. S.
    CRYSTAL RESEARCH AND TECHNOLOGY, 2007, 42 (04) : 400 - 406
  • [40] PHOTOLYSIS OF BENZO 3.4!CYCLOBUTA 1,2-B!QUINOXALINE
    SARKISIAN, JI
    BINKLEY, RW
    JOURNAL OF ORGANIC CHEMISTRY, 1970, 35 (04): : 1228 - +
12345