Synthesis and cytotoxicity studies of cyclohepta[b]indoles, benzo[6,7]cyclohepta[1,2-b]indoles, indeno[1,2-b]indoles, and benzo[a]carbazoles

被引：35

作者：

Hong, Bor-Cherng ^{[1
]}

Jiang, Yea-Fen

Chang, Yi-Ling

Lee, Shiow-Ju

机构：

[1] Natl Chung Cheng Univ, Dept Chem & Biochem, Chiayi 621, Taiwan

[2] Natl Hlth Res Inst, Div Biotechnol & Pharmaceut Res, Taipei, Taiwan

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2006年 / 53卷 / 03期

关键词：

indole; hydrazines; hydrazones; cytotoxicity; antineoplastic;

D O I：

10.1002/jccs.200600086

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthesis and biological evaluation of various tricyclic and tetracyclic indoles are described. A number of these compounds possess in vitro activity against human nasopharyngeal carcinoma (HONE-1) and gastric adenocarcinoma (NUGC-3) cell lines.

引用

页码：647 / 662

页数：16

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