The design of biopathway's modelling and simulation system based on Petri net

被引:0
作者
Ji, Chunguang
Lv, Xiancui
Li, Shiyong
机构
[1] Harbin Inst Technol, Dept Comp Sci & Technol, Harbin 150001, Peoples R China
[2] Harbin Inst Technol, Dept Control Sci & Engn, Harbin 150001, Peoples R China
来源
ROUGH SETS AND KNOWLEDGE TECHNOLOGY, PROCEEDINGS | 2006年 / 4062卷
关键词
Petri net; stochastic Petri net; modelling and simulation; biopathway;
D O I
暂无
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
The paper proposes a new software design method of biopathway's modeling and simulation application. In order for the software tool can be used by biologists easily and intuitively, we use Petri net and Stochastic Petri net to model biopathway, combining corresponding algorithms then can do deterministic and stochastic simulation, add the function that Petri net handle string, thus users can model biopathway such as transcription and translation more effectively. We introduce how to model and simulate biopathway with it in detail, it will be accepted by biologist quickly and used widely.
引用
收藏
页码:721 / 726
页数:6
相关论文
共 14 条
[1]  
[Anonymous], 1998, LECT NOTES COMPUTER
[2]  
Chuang L., 2005, STOCHASTIC PETRI NET
[3]   Efficient exact stochastic simulation of chemical systems with many species and many channels [J].
Gibson, MA ;
Bruck, J .
JOURNAL OF PHYSICAL CHEMISTRY A, 2000, 104 (09) :1876-1889
[4]   EXACT STOCHASTIC SIMULATION OF COUPLED CHEMICAL-REACTIONS [J].
GILLESPIE, DT .
JOURNAL OF PHYSICAL CHEMISTRY, 1977, 81 (25) :2340-2361
[5]   Quantitative modeling of stochastic systems in molecular biology by using stochastic Petri nets [J].
Goss, PJE ;
Peccoud, J .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (12) :6750-6755
[6]   The systems biology markup language (SBML):: a medium for representation and exchange of biochemical network models [J].
Hucka, M ;
Finney, A ;
Sauro, HM ;
Bolouri, H ;
Doyle, JC ;
Kitano, H ;
Arkin, AP ;
Bornstein, BJ ;
Bray, D ;
Cornish-Bowden, A ;
Cuellar, AA ;
Dronov, S ;
Gilles, ED ;
Ginkel, M ;
Gor, V ;
Goryanin, II ;
Hedley, WJ ;
Hodgman, TC ;
Hofmeyr, JH ;
Hunter, PJ ;
Juty, NS ;
Kasberger, JL ;
Kremling, A ;
Kummer, U ;
Le Novère, N ;
Loew, LM ;
Lucio, D ;
Mendes, P ;
Minch, E ;
Mjolsness, ED ;
Nakayama, Y ;
Nelson, MR ;
Nielsen, PF ;
Sakurada, T ;
Schaff, JC ;
Shapiro, BE ;
Shimizu, TS ;
Spence, HD ;
Stelling, J ;
Takahashi, K ;
Tomita, M ;
Wagner, J ;
Wang, J .
BIOINFORMATICS, 2003, 19 (04) :524-531
[7]   KEGG: Kyoto Encyclopedia of Genes and Genomes [J].
Kanehisa, M ;
Goto, S .
NUCLEIC ACIDS RESEARCH, 2000, 28 (01) :27-30
[8]  
MENDES P, 1993, COMPUT APPL BIOSCI, V9, P563
[9]  
Meng Tan Chee, 2004, In Silico Biol, V4, P293
[10]  
NAGASAKI M, 2004, APPL BIOINFORMATICS, V3, P181