Prenylated chalcones from Desmodium renifolium

被引：17

作者：

Li, Yan-Ping ^{[1
]}

Yang, Yu-Chun ^{[2
]}

Li, Yin-Ke ^{[2
]}

Jiang, Zhi-Yong ^{[2
]}

Huang, Xiang-Zhong ^{[2
]}

Wang, Wei-Guang ^{[3
]}

Gao, Xue-Mei ^{[2
]}

Hu, Qiu-Fen ^{[2
]}

机构：

[1] Yunnan Univ Tradit Chinese Med, Sch Pharm, Kunming 650500, Yunnan, Peoples R China

[2] Yunnan Univ Nationalities, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650031, Yunnan, Peoples R China

[3] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2014年 / 9卷

基金：

中国国家自然科学基金;

关键词：

Desmodium renifolium; Prenylated flavonoid; Prenylated chalcone; Cytotoxicity; STEM BARK; CYTOTOXIC ACTIVITIES; ANTIFUNGAL ACTIVITY; SOPHORA-FLAVESCENS; FLAVONOIDS; ANTIOXIDANT; LEAVES; DERIVATIVES; CAUDATUM; ROOTS;

D O I：

10.1016/j.phytol.2014.04.003

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new prenylated chalcones, renifolins A-C (1-3), together with seven known ones (4-10), were isolated from whole Desmodium renifolium plants. All of their structures were determined by spectroscopic methods including 1D and 2D NMR. Compounds 1 and 2 are the first naturally occurring chalcones possessing a 4-methylfuran-2(5H)-one unit. All of the isolates were evaluated for cytotoxicity using five tumor cell lines. Compounds 3-8, and 10 exhibited moderate cytotoxicity against certain cell lines with IC50 values from 4.2 to 8.8 mu M. (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

引用

页码：41 / 45

页数：5

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