Preparation of Syndiotactic Poly(vinyl alcohol) Embolic Particles with Radiopacity

被引：2
作者：
Cha, Jin Wook [1 ]
Lyoo, Won Seok [1 ]
Oh, Tae Hwan [1 ]
Han, Sung Soo [1 ]
Lee, Hae Giu [2 ]
机构：
[1] Yeungnam Univ, Dept Nano Med & Polymer Mat, Kyongsan 712749, South Korea
[2] Catholic Univ Korea, Dept Radiol, Seoul 137040, South Korea
来源：
FIBERS AND POLYMERS | 2014年 / 15卷 / 03期
关键词：
Suspension copolymerization; Radiopaque; Nanoparticles; Embolic; Poly(vinyl alcohol); SUSPENSION POLYMERIZATION; THERAPEUTIC EMBOLIZATION; CHEMICAL-MODIFICATION; VINYL PIVALATE; FOLLOW-UP; IVALON; SAPONIFICATION; MICROSPHERES; COMPOSITE; POLYMERS;
D O I：
10.1007/s12221-014-0472-9
中图分类号：
TB3 [工程材料学]; TS1 [纺织工业、染整工业];
学科分类号：
0805 ; 080502 ; 0821 ;
摘要：
A suspension copolymerization in the presence of aqueous radiopaque nanoparticles was used to prepare poly(vinyl pivalate/vinyl acetate) (P(VPi/VAc)) nanocomposite microspheres for embolic materials. To generate nanocomposite microspheres with radiopacity, various radiopaque nanoparticles (TiO2, Ti, Ag, Au and Pt) were added to P(VPi/VAc) copolymer. The P(VPi/VAc)/nanoparticles microspheres with radiopacity were then saponified in alkali solution, leading to syndiotactic poly(vinyl alcohol) (s-PVA)/nanoparticles microspheres with radiopacity of which degree of saponification (DS) was up to 99.8 %. The saponification time of P(VPi/VAc)/nanoparticles microspheres decreased with increasing the amount of nanoparticles. Computed tomography (CT) analysis revealed that s-PVA/TiO2 and s-PVA/Ti microspheres had good radiopacity.
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页码：472 / 479
页数：8
相关论文
共 30 条
[1]   RADIOPACITY OF ACRYLIC RESINS [J].
ALVARES, LC .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 1966, 22 (03) :318-&
[2]  
BARNARD CN, 1968, SURGERY, V63, P727
[3]   DENTAL ACRYLIC RESIN RADIOPACITY - LITERATURE-REVIEW AND SURVEY OF PRACTITIONERS ATTITUDES [J].
BLOODWORTH, KE ;
RENDER, PJ .
JOURNAL OF PROSTHETIC DENTISTRY, 1992, 67 (01) :121-123
[4]  
Braben M., 1988, BRIT DENT J, V164, P109
[5]   Portal vein embolization with use of polyvinyl alcohol particles [J].
Brown, KT ;
Brody, LA ;
Decorato, DR ;
Getrajdman, GI .
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2001, 12 (07) :882-886
[6]   EXPERIMENTAL-OBSERVATIONS ON SHORT AND LONG-TERM EFFECTS OF ARTERIAL-OCCLUSION WITH IVALON [J].
CASTANEDAZUNIGA, WR ;
SANCHEZ, R ;
AMPLATZ, K .
RADIOLOGY, 1978, 126 (03) :783-785
[7]  
CHANDLER H H, 1971, Journal of Biomedical Materials Research, V5, P245, DOI 10.1002/jbm.820050311
[8]   ACROLEIN AND 2-HYDROXYETHYL METHACRYLATE COPOLYMER MICROSPHERES [J].
CHANG, MC ;
COLVIN, M ;
REMBAUM, A .
JOURNAL OF POLYMER SCIENCE PART C-POLYMER LETTERS, 1986, 24 (11) :603-606
[9]   COMPARISON OF 3-POINT AND 4-POINT FLEXURAL STRENGTH TESTING OF DENTURE-BASE POLYMERS [J].
CHITCHUMNONG, P ;
BROOKS, SC ;
STAFFORD, GD .
DENTAL MATERIALS, 1989, 5 (01) :2-5
[10]   IVALON SHAVINGS - TECHNICAL CONSIDERATIONS OF A NEW EMBOLIC AGENT [J].
HERRERA, M ;
RYSAVY, J ;
KOTULA, F ;
RUSNAK, B ;
CASTANEDAZUNIGA, WR ;
AMPLATZ, K .
RADIOLOGY, 1982, 144 (03) :638-640
123