An expeditious route to 3 beta,14 beta-dihydroxy-5 beta-androstane-17 beta-carboxaldehyde

被引：5

作者：

Gobbini, M

Torri, M

机构：

[1] Prassis Ist. di Ric. Sigma-Tau SpA, 20019 Settimo Milanese (MI)

来源：

SYNTHETIC COMMUNICATIONS | 1997年 / 27卷 / 06期

关键词：

RUTHENIUM TETRAOXIDE; OXIDATION; ALCOHOLS; ACIDS;

D O I：

10.1080/00397919708003058

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and practical synthesis of 3 beta, 14 beta-dihydroxy-5 beta-androstane-17 beta-carboxaldehyde is described. The key oxidative cleavage of the unsaturated lactone of 3-acetyldigitoxigenin 1 utilises RuO4 as catalytic and NaIO4 as stoichiometric oxidants.

引用

页码：1115 / 1122

页数：8