Silent recovery of native kidney function after transplantation in a patient with membranous nephropathy

被引：5
|
作者：
Descoudres, Bernard [1 ]
Giannini, Olivier [2 ,3 ]
Aschwanden, Markus [4 ]
Eugster, Thomas [5 ]
Hopfer, Helmut [6 ]
Mihatsch, Michael J. [6 ]
Steiger, Juerg [1 ]
Mayr, Michael [1 ]
机构：
[1] Univ Basel Hosp, Clin Transplantat Immunol & Nephrol, CH-4031 Basel, Switzerland
[2] Osped Reg Beata Vergine, Serv Nephrol, Mendrisio, Switzerland
[3] Osped Reg Beata Vergine, Internal Med Serv, Mendrisio, Switzerland
[4] Univ Basel Hosp, Clin Angiol, CH-4031 Basel, Switzerland
[5] Univ Basel Hosp, Univ Vasc Ctr Aarau Basel, CH-4031 Basel, Switzerland
[6] Univ Basel Hosp, Inst Pathol, CH-4031 Basel, Switzerland
来源：
NEPHROLOGY DIALYSIS TRANSPLANTATION | 2009年 / 24卷 / 04期
关键词：
calcineurin inhibitors; kidney transplantation; membranous nephropathy; recovery of renal function; POSTTRANSPLANT LYMPHOPROLIFERATIVE DISORDER; RITUXIMAB;
D O I：
10.1093/ndt/gfn749
中图分类号：
R3 [基础医学]; R4 [临床医学];
学科分类号：
1001 ; 1002 ; 100602 ;
摘要：
Recurrence of membranous nephropathy (MN) is frequently seen after transplantation. However, there are no published data about the course of MN in the native kidneys after transplantation. Disease progression in almost all cases is assumed to be the 'natural' course after transplantation. We report on a patient suffering from end-stage renal disease due to MN. Eight years after transplantation, nephrectomy was performed due to chronic rejection and unexpectedly, partial recovery of native kidney function was noted. As far as we know, there is no other similar case reported in the literature. The potential impact of the immunosuppression, especially of calcineurin inhibitors, is discussed.
引用
收藏
页码：1345 / 1349
页数：6
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