Mobilization of qnrB2 and ISCR1 in Plasmids

被引：46
作者：
Chen, Ying-Tsong [1 ]
Liao, Tsai-Lien [1 ]
Liu, Yen-Ming [1 ]
Lauderdale, Tsai-Ling [2 ]
Yan, Jing-Jou [3 ]
Tsai, Shih-Feng [1 ,4 ,5 ,6 ,7 ]
机构：
[1] Natl Hlth Res Inst, Div Mol & Genom Med, Miaoli, Taiwan
[2] Natl Hlth Res Inst, Div Clin Res, Miaoli, Taiwan
[3] Natl Cheng Kung Univ Hosp, Dept Pathol, Tainan 70428, Taiwan
[4] Natl Yang Ming Univ, Genome Res Ctr, Taipei 112, Taiwan
[5] Natl Yang Ming Univ, Inst Biomed Informat, Taipei 112, Taiwan
[6] Natl Yang Ming Univ, Dept Life Sci, Taipei 112, Taiwan
[7] Natl Yang Ming Univ, Inst Genome Sci, Taipei 112, Taiwan
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2009年 / 53卷 / 03期
关键词：
MEDIATED QUINOLONE RESISTANCE; COMPLETE NUCLEOTIDE-SEQUENCE; ANTIBIOTIC-RESISTANCE; KLEBSIELLA-PNEUMONIAE; COMPARATIVE GENOMICS; ESCHERICHIA-COLI; TRANSPOSITION; PREVALENCE; INTEGRON; GENES;
D O I：
10.1128/AAC.00970-08
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The DNA sequences of two IncHI2 plasmids, pEC-IMP and pEC-IMPQ, from metallo-beta-lactamase-producing Enterobacter cloacae clinical isolates were determined. The two conjugative plasmids are almost identical, but pEC-IMPQ carries an additional segment containing an orf513 (ISCR1), a truncated 3' conserved sequence, and a qnrB2. Comparative analyses provide support for the proposed ISCR1-mediated gene mobilization.
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收藏
页码：1235 / 1237
页数：3
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