Integrated Micro-Optics for Microfluidic Detection

被引：10

作者：

Kazama, Yuto ^{[1
]}

Hibara, Akihide ^{[2
]}

机构：

[1] Univ Tokyo, Sch Engn, Dept Appl Chem, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138550, Japan

[2] Tokyo Inst Technol, Grad Sch Sci & Engn, Dept Chem, Meguro Ku, 2-12-1-W4-20 Ookayama, Tokyo 1528551, Japan

来源：

ANALYTICAL SCIENCES | 2016年 / 32卷 / 01期

关键词：

Microfluidics; optics; polydimethylsiloxane; embedded optics; thermal lens; TOTAL ANALYSIS SYSTEMS; PHOTOTHERMAL MICROSCOPY; POLY(DIMETHYLSILOXANE); FIELD; CHIP;

D O I：

10.2116/analsci.32.99

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A method of embedding micro-optics into a microfluidic device was proposed and demonstrated. First, the usefulness of embedded right-angle prisms was demonstrated in microscope observation. Lateral-view microscopic observation of an aqueous dye flow in a 100-mu m-sized microchannel was demonstrated. Then, the embedded right-angle prisms were utilized for multi-beam laser spectroscopy. Here, crossed-beam thermal lens detection of a liquid sample was applied to glucose detection.

引用

页码：99 / 102

页数：4

共 25 条

[1] Micro total analysis systems. 2. Analytical standard operations and applications [J].

Auroux, PA ;

Iossifidis, D ;

Reyes, DR ;

Manz, A .

ANALYTICAL CHEMISTRY, 2002, 74 (12) :2637-2652

[2] SUBMICROMETER RESOLUTION IMAGES OF ABSORBENCY AND THERMAL-DIFFUSIVITY WITH THE PHOTOTHERMAL MICROSCOPE [J].

BURGI, DS ;

DOVICHI, NJ .

APPLIED OPTICS, 1987, 26 (21) :4665-4669

[3] PDMS 2D optical lens integrated with microfluidic channels: principle and characterization [J].

Camou, S ;

Fujita, H ;

Fujii, T .

LAB ON A CHIP, 2003, 3 (01) :40-45

[4] An integrated fluorescence detection system in poly(dimethylsiloxane) for microfluidic applications [J].

Chabinyc, ML ;

Chiu, DT ;

McDonald, JC ;

Stroock, AD ;

Christian, JF ;

Karger, AM ;

Whitesides, GM .

ANALYTICAL CHEMISTRY, 2001, 73 (18) :4491-4498

[5] Compact and modular multicolour fluorescence detector for droplet microfluidics [J].

Cole, Russell H. ;

de Lange, Niek ;

Gartner, Zev J. ;

Abate, Adam R. .

LAB ON A CHIP, 2015, 15 (13) :2754-2758

[6] Thermal lens detection in microfluidic chips [J].

Dudko, V. S. ;

Smirnova, A. P. ;

Proskurnin, M. A. ;

Hibara, A. ;

Kitamori, T. .

RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2012, 82 (12) :2146-2153

[7] Micro Total Bioassay System for Oral Drugs: Evaluation of Gastrointestinal Degradation, Intestinal Absorption, Hepatic Metabolism, and Bioactivity [J].

Imura, Yuki ;

Yoshimura, Etsuro ;

Sato, Kiichi .

ANALYTICAL SCIENCES, 2012, 28 (03) :197-199

[8] Microfluidic arrays of fluid-fluid diffusional contacts as detection elements and combinatorial tools [J].

Ismagilov, RF ;

Ng, JMK ;

Kenis, PJA ;

Whitesides, GM .

ANALYTICAL CHEMISTRY, 2001, 73 (21) :5207-5213

[9]

Kazama Y., 2010, 14 INT C MIN SYST CH, V1262

[10] Quantitative and qualitative analysis of a microfluidic DNA extraction system using a nanoporous AlOx membrane [J].

Kim, Jungkyu ;

Gale, Bruce K. .

LAB ON A CHIP, 2008, 8 (09) :1516-1523

← 1 2 3 →