An Adult Case of Herpes Simplex Virus-associated Granulomatous Encephalitis

被引:1
作者
Iwai, Yuta [1 ]
Nishimura, Kazutaka [1 ]
Fukushima, Takeshi [1 ]
Ito, Takashi [1 ]
Watanabe, Yoshiyuki [2 ]
Noro, Masahiro [3 ]
Kuwabara, Satoshi [4 ]
机构
[1] Matsudo City Gen Hosp, Dept Neurol, Matsudo, Chiba, Japan
[2] Matsudo City Gen Hosp, Dept Neurosurg, Matsudo, Chiba, Japan
[3] Matsudo City Gen Hosp, Dept Pathol, Matsudo, Chiba, Japan
[4] Chiba Univ, Grad Sch Med, Dept Neurol, Chiba, Japan
关键词
granulomatous encephalitis; herpes simplex virus; reactivation; adult; acyclovir;
D O I
10.2169/internalmedicine.2046-18
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Brain granuloma occurs under certain conditions. Herpes simplex virus (HSV) causes granulomatous encephalitis in children; however, it has been rarely reported in adults. A 74-year-old man with a history of herpes simplex encephalitis suffered recurrent seizures. Brain magnetic resonance imaging revealed a mass lesion and resection was performed. A polymerase chain reaction using a brain biopsy specimen was positive for HSV DNA; thus, the patient was diagnosed with HSV-associated granulomatous encephalitis. After administering acyclovir, the patient showed improvement. HSV can cause granulomatous encephalitis in adults, and acyclovir can be used for its treatment.
引用
收藏
页码:1491 / 1494
页数:4
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