An Adult Case of Herpes Simplex Virus-associated Granulomatous Encephalitis

被引：1

作者：

Iwai, Yuta ^{[1
]}

Nishimura, Kazutaka ^{[1
]}

Fukushima, Takeshi ^{[1
]}

Ito, Takashi ^{[1
]}

Watanabe, Yoshiyuki ^{[2
]}

Noro, Masahiro ^{[3
]}

Kuwabara, Satoshi ^{[4
]}

机构：

[1] Matsudo City Gen Hosp, Dept Neurol, Matsudo, Chiba, Japan

[2] Matsudo City Gen Hosp, Dept Neurosurg, Matsudo, Chiba, Japan

[3] Matsudo City Gen Hosp, Dept Pathol, Matsudo, Chiba, Japan

[4] Chiba Univ, Grad Sch Med, Dept Neurol, Chiba, Japan

来源：

INTERNAL MEDICINE | 2019年 / 58卷 / 10期

关键词：

granulomatous encephalitis; herpes simplex virus; reactivation; adult; acyclovir;

D O I：

10.2169/internalmedicine.2046-18

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Brain granuloma occurs under certain conditions. Herpes simplex virus (HSV) causes granulomatous encephalitis in children; however, it has been rarely reported in adults. A 74-year-old man with a history of herpes simplex encephalitis suffered recurrent seizures. Brain magnetic resonance imaging revealed a mass lesion and resection was performed. A polymerase chain reaction using a brain biopsy specimen was positive for HSV DNA; thus, the patient was diagnosed with HSV-associated granulomatous encephalitis. After administering acyclovir, the patient showed improvement. HSV can cause granulomatous encephalitis in adults, and acyclovir can be used for its treatment.

引用

页码：1491 / 1494

页数：4

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