Gastrointestinal activity of Ficus sur

被引：2
|
作者：
Kunle, OO
Shittu, A
Nasipuri, RN
Kunle, OF
Wambebe, C
Akah, PA
机构：
[1] Natl Inst Pharmaceut Res & Dev, Abuja, Nigeria
[2] Univ Nigeria, Dept Pharmacol & Toxicol, Nsukka, Nigeria
来源：
FITOTERAPIA | 1999年 / 70卷 / 06期
关键词：
Ficus sur; antiulcer activity;
D O I：
10.1016/S0367-326X(99)00079-9
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The gastroprotective effects of some extracts of the dried leaves of Ficus snr in animals were investigated in order to validate the use of the plant in traditional medicine. The water and methanol extracts showed antiulcer activity, the hot water extract being the most effective. These extracts had also spasmolytic effects on the rabbit jejunum. LD50 values ranged from 900 to 1200 mg/kg in mice. These results show that F. sur has potential in the treatment of ulcers. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：542 / 547
页数：6
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