Intractable diarrhea after liver transplantation for Byler's disease: Successful treatment with bile adsorptive resin

被引：63

作者：

Egawa, H

Yorifuji, T

Sumazaki, R

Kimura, A

Hasegawa, M

Tanaka, K

机构：

[1] Kyoto Univ, Dept Transplant Surg, Kyoto, Japan

[2] Kyoto Univ, Dept Pediat, Kyoto 606, Japan

[3] Univ Tsukuba, Dept Pediat, Tsukuba, Ibaraki 305, Japan

[4] Kurume Univ, Dept Pediat, Kurume, Fukuoka 830, Japan

来源：

LIVER TRANSPLANTATION | 2002年 / 8卷 / 08期

关键词：

D O I：

10.1053/jlts.2002.34384

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Intractable diarrhea and prolonged growth retardation after liver transplantation for Byler's disease are serious complications limiting the ultimate outcome of liver transplantation for this disease. However, details of these complications have not been documented thoroughly. Six patients with Byler's disease developed intractable diarrhea after living donor liver transplantation. Because of high bile acid concentrations in stool, four patients were treated with bile acid adsorptive resin for bile acid diarrhea, and all showed improved bowel movements. Four of these patients who were followed up for 1 year registered a significant height gain. Also, the cause of postoperative diarrhea and growth retardation in patients with Byler's disease after liver transplantation is discussed.

引用

页码：714 / 716

页数：3

共 6 条

[1] A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis [J].